{"id":3573,"date":"2016-07-23T16:41:37","date_gmt":"2016-07-23T07:41:37","guid":{"rendered":"http:\/\/www.is.doshisha.ac.jp\/news\/?p=3573"},"modified":"2016-07-23T16:41:37","modified_gmt":"2016-07-23T07:41:37","slug":"%e3%80%90%e9%80%9f%e5%a0%b1%e3%80%91%e6%97%a5%e6%9c%ac%e5%85%89%e8%84%b3%e6%a9%9f%e8%83%bd%e3%82%a4%e3%83%a1%e3%83%bc%e3%82%b8%e3%83%b3%e3%82%b0%e5%ad%a6%e4%bc%9a","status":"publish","type":"post","link":"https:\/\/is.doshisha.ac.jp\/news\/?p=3573","title":{"rendered":"\u3010\u901f\u5831\u3011\u65e5\u672c\u5149\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a"},"content":{"rendered":"<p>\u65e5\u672c\u5149\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a\u304c\u3001\u661f\u9675\u4f1a\u9928\u3067\u958b\u50ac\u3055\u308c\u307e\u3057\u305f\u3002<br \/>\n\u7814\u7a76\u5ba4\u304b\u3089\u306f<\/p>\n<ul>\n<li>fNIRS\u306b\u3088\u308b\u7791\u60f3\u4e2d\u306e\u8133\u6d3b\u52d5\u306e\u8a08\u6e2c\u3000\u85e4\u4e95\u8056\u9999\u3000(B4)<\/li>\n<li><\/li>\n<\/ul>\n<p>\u304c\u767a\u8868\u3057\u307e\u3057\u305f\u3002<br \/>\n<!--more--><br \/>\n<strong>\u5b66\u4f1a\u53c2\u52a0\u5831\u544a\u66f8<\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"147\"><strong>\u00a0<\/strong><strong>\u5831\u544a\u8005\u6c0f\u540d<\/strong><\/td>\n<td width=\"373\">\u85e4\u4e95\u8056\u9999<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u767a\u8868\u8ad6\u6587\u30bf\u30a4\u30c8\u30eb<\/strong><\/td>\n<td width=\"373\">fNIRS\u306b\u3088\u308b\u7791\u60f3\u4e2d\u306e\u8133\u6d3b\u52d5\u306e\u8a08\u6e2c<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u767a\u8868\u8ad6\u6587\u82f1\u30bf\u30a4\u30c8\u30eb<\/strong><\/td>\n<td width=\"373\">Conference Report<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u8457\u8005<\/strong><\/td>\n<td width=\"373\">\u85e4\u4e95\u8056\u9999, \u65e5\u548c\u609f, \u5ee3\u5b89\u77e5\u4e4b<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u4e3b\u50ac<\/strong><\/td>\n<td width=\"373\">\u4e00\u822c\u793e\u56e3\u6cd5\u4eba \u65e5\u672c\u5149\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u8b1b\u6f14\u4f1a\u540d<\/strong><\/td>\n<td width=\"373\">\u4e00\u822c\u793e\u56e3\u6cd5\u4eba \u65e5\u672c\u5149\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a\u7b2c19\u56de\u5b66\u8853\u96c6\u4f1a<br \/>\nhttp:\/\/jofbis.umin.jp\/rally-019.html<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u4f1a\u5834<\/strong><\/td>\n<td width=\"373\">\u661f\u9675\u4f1a\u9928\uff08\u6771\u4eac\u90fd\u5343\u4ee3\u7530\u533a\u6c38\u7530\u753a2-16-2\uff09<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u958b\u50ac\u65e5\u7a0b<\/strong><\/td>\n<td width=\"373\">2016\/07\/23<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<br \/>\n&nbsp;<\/p>\n<ol>\n<li>\u8b1b\u6f14\u4f1a\u306e\u8a73\u7d30<\/li>\n<\/ol>\n<p>2016\/07\/23\u306b\uff0c\u6771\u4eac\u306e\u661f\u9675\u4f1a\u9928\u306b\u3066\u958b\u50ac\u3055\u308c\u307e\u3057\u305f\u65e5\u672c\u5149\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a\u7b2c19\u56de\u5b66\u8853\u96c6\u4f1a\u306b\u53c2\u52a0\u3044\u305f\u3057\u307e\u3057\u305f\uff0e\u3053\u306e\u65e5\u672c\u5149\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a\u7b2c19\u56de\u5b66\u8853\u96c6\u4f1a\u306f\uff0c\u4e00\u822c\u793e\u56e3\u6cd5\u4eba \u65e5\u672c\u5149\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a\u306b\u3088\u3063\u3066\u4e3b\u50ac\u3055\u308c\u305f\u5b66\u8853\u96c6\u4f1a\u3067\uff0c\u5b66\u751f\u3084\u5927\u5b66\u6559\u6388\uff0c\u4f01\u696d\u304c\u53c2\u52a0\u3057\u3066\u304a\u308a\u307e\u3057\u305f\uff0e\u65e5\u672c\u304c\u4e16\u754c\u306b\u5148\u99c6\u3051\u3066\u958b\u767a\u3057\u305f\u8fd1\u8d64\u5916\u7dda\u5206\u5149\u6cd5\u3092\u5229\u7528\u3057\u305f\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u6cd5\u306e\u7814\u7a76\u3092\u81e8\u5e8a\u5fdc\u7528\u306a\u3069\u306b\u4fc3\u9032\u3057\u3001\u533b\u7642\u306e\u767a\u5c55\u306b\u5bc4\u4e0e\u3057\u3001\u5e83\u304f\u56fd\u6c11\u306e\u5065\u5eb7\u5897\u9032\u306b\u8ca2\u732e\u3059\u308b\u305f\u3081\u306e\u8b70\u8ad6\u3092\u884c\u3044\uff0c\u3053\u306e\u5149\u306b\u3088\u308b\u8133\u6a5f\u80fd\u8a08\u6e2c\u6cd5\u306e\u57fa\u790e\u7814\u7a76\u3092\u3055\u3089\u306b\u6df1\u3081\uff0c\u3088\u308a\u767a\u5c55\u3057\u78ba\u7acb\u3057\u305f\u6280\u8853\u3068\u3057\u3066\u8133\u6a5f\u80fd\u306e\u7814\u7a76\u3084\u81e8\u5e8a\u5fdc\u7528\u306b\u5b9a\u7740\u3055\u305b\u308b\u3053\u3068\u3092\u76ee\u7684\u306b\u958b\u50ac\u3055\u308c\u3066\u3044\u307e\u3059\uff0e<br \/>\n\u672c\u7814\u7a76\u5ba4\u304b\u3089\u306f\u4ed6\u306b\u65e5\u548c\u5148\u751f\uff0cM1\u306e\u5409\u6b66\u3055\u3093\u304c\u53c2\u52a0\u3055\u308c\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<ol start=\"2\">\n<li>\u7814\u7a76\u767a\u8868\n<ul>\n<li>\u767a\u8868\u6982\u8981<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n<p>\u79c1\u306f23\u65e5\u306e\u5348\u5f8c\u306e\u30bb\u30c3\u30b7\u30e7\u30f3\u300c\u30d5\u30e9\u30c3\u30b7\u30e5\u30c8\u30fc\u30af\u300d\uff0c\u300c\u30dd\u30b9\u30bf\u30fc\u767a\u8868\u300d\u306b\u53c2\u52a0\u3044\u305f\u3057\u307e\u3057\u305f\uff0e\u767a\u8868\u306e\u5f62\u5f0f\u306f\u53e3\u982d\u767a\u8868\u3067\uff0c2\u520630\u79d2\u306e\u30d5\u30e9\u30c3\u30b7\u30e5\u30c8\u30fc\u30af\u3068\u7d041\u6642\u9593\u306e\u30dd\u30b9\u30bf\u30fc\u767a\u8868\u3068\u306a\u3063\u3066\u304a\u308a\u307e\u3057\u305f\uff0e<br \/>\n\u4eca\u56de\u306e\u767a\u8868\u306f\u300cfNIRS\u306b\u3088\u308b\u7791\u60f3\u4e2d\u306e\u8133\u6d3b\u52d5\u3092\u8a08\u6e2c\u300d\u3068\u3044\u3046\u984c\u3067\u767a\u8868\u3044\u305f\u3057\u307e\u3057\u305f\uff0e\u4ee5\u4e0b\u306b\u6284\u9332\u3092\u8a18\u8f09\u81f4\u3057\u307e\u3059\uff0e<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"529\">\u300c\u30de\u30a4\u30f3\u30c9\u30d5\u30eb\u30cd\u30b9\u300d\u3068\u306f\uff0c\u300c\u4eca\u8d77\u304d\u3066\u3044\u308b\u3053\u3068\u306b\u80fd\u52d5\u7684\u306b\u6ce8\u610f\u3092\u5411\u3051\u308b\u3053\u3068\u300d\u3067\u3042\u308a\uff0c\u305d\u306e\u5b9f\u73fe\u624b\u6bb5\u3068\u3057\u3066\u30de\u30a4\u30f3\u30c9\u30d5\u30eb\u30cd\u30b9\u7791\u60f3\u304c\u6319\u3052\u3089\u308c\u308b\uff0e\u30de\u30a4\u30f3\u30c9\u30d5\u30eb\u30cd\u30b9\u7791\u60f3\u306f\u30b9\u30c8\u30ec\u30b9\u4f4e\u6e1b\u3084\u96c6\u4e2d\u529b\u5411\u4e0a\u306e\u52b9\u679c\u304c\u3042\u308b\u305f\u3081\uff0c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\uff0e\u305d\u3053\u3067\uff0c\u8457\u8005\u3089\u306f\u30de\u30a4\u30f3\u30c9\u30d5\u30eb\u30cd\u30b9\u7791\u60f3\u306e\u6ce8\u610f\u5236\u5fa1\u306e\u6a5f\u80fd\u306b\u6ce8\u76ee\u3057\uff0c\u7791\u60f3\u7d4c\u9a13\u306e\u7121\u3044\u521d\u5fc3\u8005\u304c\u6570\u606f\u89b3\u3068\u3044\u3046\u7c21\u6613\u306a\u7791\u60f3\u306b\u3088\u3063\u3066\u3069\u306e\u3088\u3046\u306a\u52b9\u679c\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u304b\u3092\u691c\u8a0e\u3057\u305f\uff0e<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<br \/>\n&nbsp;<\/p>\n<ul>\n<li>\u8cea\u7591\u5fdc\u7b54<\/li>\n<\/ul>\n<p>\u4eca\u56de\u306e\u30dd\u30b9\u30bf\u30fc\u767a\u8868\u3067\u306f\uff0c\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u8cea\u7591\u3092\u53d7\u3051\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<br \/>\n<strong>\u30fb\u8cea\u554f\u5185\u5bb9<\/strong><strong>1<\/strong><br \/>\n\u68ee\u672c\u3055\u3093\u304b\u3089\u306e\u8cea\u554f\u3067\u3059\uff0e\u3053\u3061\u3089\u306e\u8cea\u554f\u306f\uff0c\u5fc3\u62cd\u306f\u3068\u3089\u306a\u3044\u306e\u304b\u3068\u3044\u3046\u3082\u306e\u3067\u3057\u305f\uff0e\u3053\u306e\u8cea\u554f\u306b\u5bfe\u3059\u308b\u79c1\u306e\u56de\u7b54\u3067\u3059\u304c\uff0c\u5fc3\u62cd\u306b\u3064\u3044\u3066\u306f\u5168\u304f\u982d\u306b\u306a\u304b\u3063\u305f\u3068\u56de\u7b54\u3044\u305f\u3057\u307e\u3057\u305f\uff0e\u307e\u305f\uff0c\u6570\u606f\u89b3\u3092\u884c\u3046\u3053\u3068\u306b\u3088\u3063\u3066\uff0c\u5fc3\u304c\u843d\u3061\u7740\u3044\u305f\u3068\u3044\u3046\u88ab\u9a13\u8005\u306e\u58f0\u3082\u3042\u308a\uff0c\u5fc3\u62cd\u3082\u4f75\u305b\u3066\u307f\u308c\u3070\u304a\u3082\u3057\u308d\u3044\u304b\u3082\u3057\u308c\u306a\u3044\u3068\u56de\u7b54\u3044\u305f\u3057\u307e\u3057\u305f\uff0e\u3059\u3050\u508d\u3067\u30dd\u30b9\u30bf\u30fc\u3092\u898b\u306b\u304d\u3066\u304f\u3060\u3055\u3063\u305f\u65e5\u7acb\u306e\u6842\u3055\u3093\u306b2CH\u306eNIRS\u3092\u7528\u3044\u308c\u3070\u8133\u8840\u6d41\u3082\u5fc3\u62cd\u3082\u3068\u308c\u308b\u3068\u3044\u3046\u30a2\u30c9\u30d0\u30a4\u30b9\u3092\u3044\u305f\u3060\u304d\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<br \/>\n<strong>\u30fb\u8cea\u554f\u5185\u5bb9<\/strong><strong>2<\/strong><br \/>\n\u8cea\u554f\u8005\u306e\u6c0f\u540d\u3092\u63a7\u3048\u640d\u306d\u3066\u3057\u307e\u3044\u307e\u3057\u305f\uff0e\u8cea\u554f\u306f\u8ab2\u984c\u6642\u3068\u5b89\u9759\u6642\u306e\u6642\u9593\u3092\u3082\u3063\u3068\u9577\u304f\u3057\u306a\u3044\u306e\u306f\u306a\u305c\u304b\uff0c\u5b66\u7fd2\u30bb\u30c3\u30b7\u30e7\u30f3\u3092\u53d6\u308a\u5165\u308c\u3066\u307f\u3066\u306f\u3069\u3046\u3060\u308d\u3046\u304b\u3068\u3044\u3046\u3082\u306e\u3067\u3057\u305f\uff0e\u3053\u306e\u8cea\u554f\u306b\u5bfe\u3059\u308b\u56de\u7b54\u3067\u3059\u304c\uff0cfNIRS\u3092\u9577\u6642\u9593\u88ab\u9a13\u8005\u306b\u88c5\u7740\u3057\u3066\u304a\u304f\u3068\u75b2\u308c\u304c\u51fa\u3066\u3057\u307e\u3046\u305f\u3081\u3068\u56de\u7b54\u3044\u305f\u3057\u307e\u3057\u305f\uff0e\u3057\u304b\u3057\uff0c\u8ab2\u984c\u6642\u3068\u5b89\u9759\u6642\u306e\u6642\u9593\u306b\u3064\u3044\u3066\u306f\u81ea\u5206\u81ea\u8eab\u3082\u3082\u3046\u5c11\u3057\u9577\u304f\u3068\u308a\u305f\u3044\u3068\u601d\u3063\u3066\u3044\u305f\u306e\u3067\uff0c\u5b9f\u9a13\u8a2d\u8a08\u306b\u3064\u3044\u3066\u306f\u898b\u76f4\u3057\u3066\u3044\u304d\u305f\u3044\u3068\u3082\u56de\u7b54\u3057\u307e\u3057\u305f\uff0e\u307e\u305f\uff0c\u5b66\u7fd2\u30bb\u30c3\u30b7\u30e7\u30f3\u306b\u3064\u3044\u3066\u306e\u56de\u7b54\u3067\u3059\u304c\uff0c\u305c\u3072\u3084\u3063\u3066\u307f\u305f\u3044\u3068\u56de\u7b54\u3057\u307e\u3057\u305f\uff0e\u3057\u304b\u3057\uff0c\u5f8c\u307b\u3069\u306e\u8b70\u8ad6\u3067\u521d\u5fc3\u8005\u3068\u7d4c\u9a13\u8005\u306e\u7dda\u5f15\u304d\u7b49\u5b66\u751f\u5b9f\u9a13\u3067\u306f\u56f0\u96e3\u3067\u3042\u308b\u3068\u8003\u3048\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<ul>\n<li>\u611f\u60f3<\/li>\n<\/ul>\n<p>\u521d\u3081\u3066\u306e\u5b66\u4f1a\uff0c\u521d\u3081\u3066\u306e\u30dd\u30b9\u30bf\u30fc\u767a\u8868\u3067\u3068\u3066\u3082\u7dca\u5f35\u3057\u307e\u3057\u305f\uff0e\u30d5\u30e9\u30c3\u30b7\u30e5\u30c8\u30fc\u30af\u3067\u306f\u601d\u3063\u3066\u3044\u305f\u3088\u308a\u3082\u7dca\u5f35\u3059\u308b\u3053\u3068\u306a\u304f\u81e8\u3080\u3053\u3068\u304c\u3067\u304d\u307e\u3057\u305f\u304c\uff0c\u9014\u4e2d\u3067\u8a71\u3059\u5185\u5bb9\u304c\u98db\u3093\u3067\u3057\u307e\u3063\u305f\u3068\u3053\u308d\u3082\u3042\u308a\uff0c\u5f8c\u534a\u306f\u5c11\u3057\u7126\u3063\u3066\u3057\u307e\u3044\u307e\u3057\u305f\uff0e\u30dd\u30b9\u30bf\u30fc\u767a\u8868\u3067\u306f\uff0c\u7791\u60f3\u3092\u8ab2\u984c\u3068\u3057\u3066\u6271\u3063\u305f\u3053\u3068\u306b\u8208\u5473\u3092\u6301\u3063\u3066\u6765\u3066\u304f\u3060\u3055\u3063\u305f\u65b9\u3082\u591a\u304f\u307f\u3089\u308c\u307e\u3057\u305f\uff0e\u306a\u304b\u306a\u304b\uff0c\u3046\u307e\u304f\u8a71\u3059\u3053\u3068\u304c\u3067\u304d\u305a\uff0c\u65e5\u548c\u5148\u751f\u306e\u304a\u529b\u3082\u501f\u308a\u306a\u304c\u3089\u3068\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3057\u305f\u304c\uff0c\u4ed6\u5927\u5b66\u306e\u6559\u6388\u3084\uff0c\u5b66\u751f\uff0c\u4f01\u696d\u306e\u65b9\u3068\u8b70\u8ad6\u3059\u308b\u3053\u3068\u304c\u3067\u304d\uff0c\u3053\u308c\u304b\u3089\u306e\u7814\u7a76\u306b\u53cd\u6620\u3055\u305b\u3066\u3044\u304d\u305f\u3044\u3068\u601d\u3044\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<ol start=\"3\">\n<li>\u8074\u8b1b<\/li>\n<\/ol>\n<p>\u4eca\u56de\u306e\u8b1b\u6f14\u4f1a\u3067\u306f\uff0c\u4e0b\u8a18\u306e2\u4ef6\u306e\u767a\u8868\u3092\u8074\u8b1b\u3057\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"529\">\u767a\u8868\u30bf\u30a4\u30c8\u30eb\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a\u3000fNIRS\u3067\u8a55\u4fa1\u3059\u308b\u5b66\u7fd2\u306b\u3088\u308b\u8133\u306e\u53ef\u5851\u7684\u5909\u5316\u8457\u8005\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u7686\u5ddd\u6cf0\u4ee3<br \/>\n\u30bb\u30c3\u30b7\u30e7\u30f3\u540d\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u5927\u4f1a\u9577\u8b1b\u6f14<br \/>\nAbstruct\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u5150\u7ae5\u671f\u304b\u3089\u9752\u5e74\u671f\u305d\u3057\u3066\u6210\u4eba\u671f\u306b\u3044\u305f\u308b\u307e\u3067\u306b\u8a8d\u77e5\u6a5f\u80fd\u306f\u767a\u9054\u3000\u3000\u3057\uff0c\u305d\u308c\u306b\u3068\u3082\u306a\u3063\u3066\u5927\u8133\u306e\u69cb\u9020\u3084\u6a5f\u80fd\u3082\u5927\u304d\u304f\u5909\u5316\u3059\u308b\uff0e\u8a00\u8a9e\u5b66\u7fd2\uff08\u7fd2\u5f97\uff09\u306e\u81e8\u754c\u671f\u3068\u3044\u3046\u8a00\u8449\u304c\u793a\u3059\u3068\u304a\u308a\u8a00\u8a9e\u306e\u5b66\u7fd2\u3068\u3044\u3046\u8a8d\u77e5\u6a5f\u80fd\u3092\u4f8b\u306b\u3068\u3063\u3066\u3082\u305d\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306f\u5e74\u9f62\u3068\u3068\u3082\u306b\u5287\u7684\u306b\u5909\u5316\u3059\u308b\u304c\uff0c\u305d\u306e\u5b66\u7fd2\u6a5f\u69cb\u306b\u95a2\u4e0e\u3059\u308b\u8133\u8133\u6a5f\u69cb\u306e\u767a\u9054\u5909\u5316\u306b\u3064\u3044\u3066\u306f\u591a\u304f\u306f\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u306a\u3044\uff0e\u3053\u308c\u306f\u767a\u9054\u671f\u306e\u8133\u3092\u691c\u8a0e\u3059\u308b\u624b\u6cd5\u306b\u69d8\u3005\u306a\u5236\u7d04\u304c\u3042\u3063\u305f\u3053\u3068\u306b\u3082\u3088\u308b\u3068\u601d\u308f\u308c\u308b\uff0e\u672c\u8b1b\u6f14\u3067\u306f\u767a\u9054\u8133\u3092\u6bd4\u8f03\u7684\u7c21\u4fbf\u306b\u8a08\u6e2c\u3067\u304d\u308bfNIRS(functional Neat Infrared Spectroscopy)\u3092\u7528\u3044\u3066\uff0c\u767a\u9054\u671f\u306e\u5b66\u7fd2\u6a5f\u69cb\u306b\u95a2\u4e0e\u3059\u308b\u8133\u5185\u6a5f\u69cb\u3092\u691c\u8a0e\u3057\u305f\u4e00\u9023\u306e\u7814\u7a76\u306b\u3064\u3044\u3066\u6982\u8aac\u3059\u308b\uff0e\u65b0\u751f\u5150\u671f\uff0c\u5b66\u7ae5\u671f\uff0c\u601d\u6625\u671f\uff0c\u524d\u6210\u4eba\u671f\u306e\u5404\u767a\u9054\u30b9\u30c6\u30fc\u30b8\u306b\u304a\u3044\u3066\uff0c\u5b66\u7fd2\u306b\u3068\u3082\u306a\u3063\u3066\u3069\u306e\u3088\u3046\u306b\u8133\u5185\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u304c\u518d\u7de8\u6210\u3055\u308c\u308b\u304b\u3092\u6982\u89b3\u3057\uff0c\u767a\u9054\u306b\u3088\u308b\u8133\u306e\u53ef\u5851\u6027\u306e\u5909\u5316\u306b\u3064\u3044\u3066\u8003\u5bdf\u3059\u308b\uff0e<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u3053\u306e\u767a\u8868\u306f\u4eca\u56de\u79c1\u3082\u30dd\u30b9\u30bf\u30fc\u767a\u8868\u306b\u3066\u3068\u308a\u3042\u3052\u305f\u8133\u6a5f\u80fd\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3092\u7528\u3044\u305f\u7814\u7a76\u3067\u3042\u308a\uff0c<br \/>\n\u3068\u3066\u3082\u53c2\u8003\u306b\u306a\u308a\u307e\u3057\u305f\uff0e\u30b3\u30cd\u30af\u30c6\u30a3\u30d3\u30c6\u30a3\u306f\uff0c\u751f\u307e\u308c\u3066\u304b\u3089\u6210\u4eba\u306b\u306a\u308b\u307e\u3067\u306b\u5897\u52a0\u3057\uff0c\u30d4\u30fc\u30af\u3092\u8fce\u3048\u305f\u3068\u3053\u308d\u3067\u305d\u306e\u5f8c\u6e1b\u5c11\u3057\u3066\u3044\u304f\u3068\u3044\u3046\u63a8\u8ad6\u306b\u3068\u3066\u3082\u8208\u5473\u3092\u6301\u3061\u307e\u3057\u305f\uff0e\u307e\u305f\uff0c\u65b0\u751f\u5150\u306e\u5b89\u9759\u6642\u306e\u6d3b\u52d5\u306b\u3064\u3044\u3066\u306e\u8b1b\u6f14\u3092\u3042\u308a\uff0c\u65b0\u751f\u5150\u306f\u30b3\u30cd\u30af\u30c6\u30a3\u30d3\u30c6\u30a3\u304c\u304b\u306a\u308a\u591a\u304f\uff0c\u305d\u306e\u7406\u7531\u306b\u3064\u3044\u3066\u306f\u7814\u7a76\u6bb5\u968e\u3068\u3044\u3046\u3053\u3068\u3067\u3057\u305f\uff0e\u6b21\u56de\u306e\u5b66\u8853\u96c6\u4f1a\u3067\u305d\u306e\u8003\u5bdf\u304c\u305c\u3072\u8074\u3051\u305f\u3089\u3068\u601d\u3044\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"529\">\u767a\u8868\u30bf\u30a4\u30c8\u30eb\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a\u5149\u8a08\u6e2c\u306b\u3088\u308a\u53ef\u8996\u5316\u3059\u308b\u767a\u9054\u8133\u306e\u6a5f\u80fd\u7684\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u8457\u8005\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u4fdd\u524d\u6587\u9ad8<br \/>\n\u30bb\u30c3\u30b7\u30e7\u30f3\u540d\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u62db\u5f85\u8b1b\u6f14<br \/>\nAbstruct\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0\uff1a \u672c\u8b1b\u6f14\u3067\u306f\uff0c\u4e73\u5150\u3092\u5bfe\u8c61\u3068\u3057\u305fNIRS\u8a08\u6e2c\u306e\u7d50\u679c\u3092\u3082\u3068\u306b\u3057\u3066\uff0c\u81ea\u767a\u6d3b\u52d5\u3067\u89b3\u6e2c\u3055\u308c\u308b\u3088\u3046\u306a\u57fa\u5e79\u3068\u306a\u308b\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u304c\u60c5\u5831\u51e6\u7406\u4f9d\u5b58\u7684\u306b\u4fee\u98fe\u3055\u308c\u308b\u3053\u3068\u3067\u7279\u5b9a\u306e\u6a5f\u80fd\u306b\u304b\u304b\u308f\u308b\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u304c\u5f62\u6210\u3055\u308c\u308b\u3068\u3044\u3046\u4eee\u8aac\u3092\u63d0\u6848\u3059\u308b\uff0e\u307e\u305f\uff0c\u6a5f\u80fd\u7684\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3067\u4e2d\u5fc3\u7684\u306a\u5f79\u5272\u3092\u679c\u305f\u3059\uff08\u30cf\u30d6\uff09\u9818\u57df\u3092\u540c\u5b9a\u3059\u308b\u3053\u3068\u306b\u3088\u308a\uff0c\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3092\u691c\u8a0e\u3059\u308b\u3053\u3068\u304c\u304b\u3048\u3063\u3066\u5c40\u5728\u6027\u3092\u9855\u5728\u5316\u3055\u305b\u308b\u3053\u3068\u306b\u3082\u6ce8\u76ee\u3059\u308b\uff0e\u3053\u306e\u3088\u3046\u306a\u4e2d\u5fc3\u6027\u306e\u9ad8\u3044\u9818\u57df\u304c\u3069\u306e\u9818\u57df\u3068\u6a5f\u80fd\u7684\u7d50\u5408\u3092\u6709\u3059\u308b\u304b\u306b\u306f\uff0c\u4e73\u5150\u306e\u767a\u9054\u904e\u7a0b\u306b\u304a\u3051\u308b\u300c\u500b\u6027\u300d\u304c\u3042\u3089\u308f\u308c\u308b\u3068\u3044\u3046\u53ef\u80fd\u6027\u306b\u3064\u3044\u3066\u3082\u8b70\u8ad6\u3059\u308b\uff0e<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u3053\u3061\u3089\u306e\u767a\u8868\u3082\u8133\u6a5f\u80fd\u306e\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3092\u691c\u8a0e\u3057\u305f\u7814\u7a76\u3067\u3057\u305f\uff0e\u79c1\u3082\u3053\u308c\u304b\u3089\u3088\u308a\u8a73\u3057\u304f\u691c\u8a0e\u3057\u305f\u3044\u3068\u601d\u3063\u3066\u3044\u305f\u56fa\u6709\u30d9\u30af\u30c8\u30eb\u4e2d\u5fc3\u6027\u306b\u3064\u3044\u3066\u306e\u8b70\u8ad6\u3067\u3042\u308a\uff0c\u81ea\u5206\u306e\u7814\u7a76\u306b\u3068\u3066\u3082\u53c2\u8003\u306b\u306a\u308b\u3088\u3046\u306a\u5185\u5bb9\u3067\u3057\u305f\uff0e\u30cf\u30d6\u3068\u306a\u3063\u3066\u3044\u308b\u90e8\u4f4d\u306e\u76f8\u95a2\u306e\u500b\u4eba\u5dee\u306f\u5c0f\u3055\u3044\u3068\u3044\u3046\u3053\u3068\u3067\uff0c\u305d\u3053\u304b\u3089\u3069\u3053\u3078\u7d50\u5408\u3057\u3066\u3044\u308b\u304b\u304c\u300c\u500b\u6027\u300d\u306a\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u8003\u3048\u307e\u3057\u305f\uff0e\u3057\u304b\u3057\uff0cfNIRS\u3067\u8a08\u6e2c\u3057\u305f\u8868\u9762\u306b\u30cf\u30d6\u304c\u3042\u308b\u3068\u3044\u3063\u3066\u3044\u3044\u306e\u304b\uff0c\u6df1\u90e8\u306b\u3042\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u3044\u3046\u8b70\u8ad6\u3067fMRI\u3068\u306e\u540c\u6642\u8a08\u6e2c\u306e\u8a71\u3082\u51fa\u3066\u304a\u308a\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<br \/>\n\u53c2\u8003\u6587\u732e<\/p>\n<ul>\n<li>\u4e00\u822c\u793e\u56e3\u6cd5\u4eba \u65e5\u672c\u5149\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a, http:\/\/jofbis.umin.jp\/index.html<\/li>\n<\/ul>\n<p><strong>\u5b66\u4f1a\u53c2\u52a0\u5831\u544a\u66f8<\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"147\"><strong>\u5831\u544a\u8005\u6c0f\u540d<\/strong><\/td>\n<td width=\"373\">\u5409\u6b66\u6c99\u898f<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u767a\u8868\u8ad6\u6587\u30bf\u30a4\u30c8\u30eb<\/strong><\/td>\n<td width=\"373\">GLM analysis to fNIRS data during N-back task using adaptive HRF<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u767a\u8868\u8ad6\u6587\u82f1\u30bf\u30a4\u30c8\u30eb<\/strong><\/td>\n<td width=\"373\">GLM analysis to fNIRS data during N-back task using adaptive HRF<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u8457\u8005<\/strong><\/td>\n<td width=\"373\">\u5409\u6b66\u6c99\u898f, \u5ee3\u5b89\u77e5\u4e4b, \u65e5\u548c\u609f<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u4e3b\u50ac<\/strong><\/td>\n<td width=\"373\">\u533b\u7642\u60c5\u5831\u30b7\u30b9\u30c6\u30e0\u7814\u7a76\u5ba4<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u8b1b\u6f14\u4f1a\u540d<\/strong><\/td>\n<td width=\"373\">\u7b2c19\u56de\u5149\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u4f1a\u5834<\/strong><\/td>\n<td width=\"373\">\u661f\u9675\u4f1a\u9928<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u958b\u50ac\u65e5\u7a0b<\/strong><\/td>\n<td width=\"373\">2016\/07\/23<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<br \/>\n&nbsp;<\/p>\n<ol>\n<li>\u8b1b\u6f14\u4f1a\u306e\u8a73\u7d30<\/li>\n<\/ol>\n<p>2016\/07\/23\u306b\u661f\u9675\u4f1a\u9928\u3067\u958b\u50ac\u3055\u308c\u307e\u3057\u305f\u7b2c19\u56de\u5149\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a\u306b\u53c2\u52a0\u81f4\u3057\u307e\u3057\u305f\uff0e\u3053\u306e\u5149\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a\u306f\u65e5\u672c\u5149\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a\u304c\u958b\u50ac\u3059\u308b\u5b66\u8853\u96c6\u4f1a\u3067\uff0c\u8fd1\u8d64\u5916\u5149\u306b\u3088\u308b\u8133\u6a5f\u80fd\u8a08\u6e2c\u6cd5\u306e\u57fa\u790e\u7814\u7a76\u3092\u6df1\u3081\u3001\u78ba\u7acb\u3057\u305f\u6280\u8853\u3068\u3057\u3066\u8133\u6a5f\u80fd\u306e\u7814\u7a76\u3084\u81e8\u5e8a\u5fdc\u7528\u306b\u5b9a\u7740\u3055\u305b\u308b\u305f\u3081\u3001\u7814\u7a76\u8005\u9593\u306e\u60c5\u5831\u4ea4\u63db\uff0c\u7814\u7a76\u5354\u529b\u3092\u4fc3\u9032\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u958b\u50ac\u3055\u308c\u3066\u3044\u307e\u3059\uff0e<br \/>\n\u672c\u7814\u7a76\u5ba4\u304b\u3089\u306f\u4ed6\u306b\u5ee3\u5b89\u5148\u751f\uff0c\u65e5\u548c\u5148\u751f\uff0c\u85e4\u4e95\u304c\u53c2\u52a0\u3057\u307e\u3057\u305f\uff0e<\/p>\n<ol start=\"2\">\n<li>\u7814\u7a76\u767a\u8868\n<ul>\n<li>\u767a\u8868\u6982\u8981<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n<p>\u79c1\u306f\u5348\u5f8c\u306b\u958b\u50ac\u3055\u308c\u305f\u30dd\u30b9\u30bf\u30fc\u767a\u8868\u306b\u53c2\u52a0\u3057\u307e\u3057\u305f\uff0e<br \/>\n\u30dd\u30b9\u30bf\u30fc\u524d\u3067\u306e\u8b70\u8ad6\u304c\u884c\u308f\u308c\uff0c\u30dd\u30b9\u30bf\u30fc\u306e\u6982\u8981\u3092\u767a\u8868\u3059\u308b2\u520630\u79d2\u306e\u30d5\u30e9\u30c3\u30b7\u30e5\u30c8\u30fc\u30af\u3092\u884c\u3044\u307e\u3057\u305f\uff0e<br \/>\n\u4eca\u56de\u306e\u767a\u8868\u306f\uff0cfNIRS\u30c7\u30fc\u30bf\u306e\u89e3\u6790\u65b9\u6cd5\u306b\u3064\u3044\u3066\u306e\u7814\u7a76\u3092\u884c\u3044\u307e\u3057\u305f\uff0e<br \/>\n\u30a2\u30d6\u30b9\u30c8\u30e9\u30af\u30c8\u3092\u4ee5\u4e0b\u306b\u793a\u3057\u307e\u3059<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"529\">[\u80cc\u666f]<br \/>\nNIRS\u8133\u8a08\u6e2c\u88c5\u7f6e\uff08fNIRS\uff09\u306f\uff0c\u8133\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u88c5\u7f6e\u3067\u3042\u308a\uff0c\u8fd1\u5e74\u5e83\u304f\u4f7f\u7528\u3055\u308c\u3066\u3044\u308b\uff0e\u8133\u6a5f\u80fd\u6d3b\u6027\u306f\uff0c\u8840\u6d41\u91cf\u5909\u5316\u3092\u6e2c\u5b9a\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u6c7a\u5b9a\u3055\u308c\u308b\uff0e\u4e00\u822c\u5316\u7dda\u5f62\u30e2\u30c7\u30eb\uff08GLM\uff09\u306f\uff0c\u8133\u6a5f\u80fd\u6d3b\u6027\u3092\u5206\u6790\u3059\u308b\u65b9\u6cd5\u306e\u4e00\u3064\u3067\u3042\u308a\uff0c\u6a5f\u80fd\u7684\u78c1\u6c17\u5171\u9cf4\u753b\u50cf\u6cd5\uff08fMRI\uff09\u5206\u6790\u306b\u3082\u4f7f\u7528\u3055\u308c\u308b\uff0eGLM\u306b\u304a\u3044\u3066\u6d3b\u6027\u306f\uff0c\u57fa\u5e95\u95a2\u6570\u3068\u30c6\u30b9\u30c8\u30c7\u30fc\u30bf\u3068\u306e\u56de\u5e30\u5206\u6790\u306e\u985e\u4f3c\u6027\u306b\u3088\u3063\u3066\u6c7a\u5b9a\u3055\u308c\u308b\uff0e\u57fa\u5e95\u95a2\u6570\u306f\uff0c\u77e9\u5f62\u95a2\u6570\u3068\u8840\u6d41\u52d5\u614b\u53cd\u5fdc\u95a2\u6570\uff08HRF\uff09\u3092\u7573\u307f\u8fbc\u3080\u3053\u3068\u306b\u3088\u3063\u3066\u751f\u6210\u3055\u308c\uff0c\u4e00\u822c\u306b\u6642\u9593\u5909\u6570\u304c\u30d1\u30e9\u30e1\u30fc\u30bf\u306b\u4f7f\u7528\u3055\u308c\u308b\uff0e HRF\u306f\uff0c\u6700\u521d\u306e\u30d4\u30fc\u30af\u9045\u5ef6\uff0c\u7b2c2\u306e\u30d4\u30fc\u30af\u9045\u5ef6\u3068\u7b2c1\u53ca\u3073\u7b2c2\u306e\u30d4\u30fc\u30af\u306e\u6bd4\u306a\u3069\u306e\u3044\u304f\u3064\u304b\u306e\u30d1\u30e9\u30e1\u30fc\u30bf\u3092\u6301\u3063\u3066\u3044\u308b\uff0e\u77e9\u5f62\u95a2\u6570\u306f\uff0c\u5b9f\u9a13\u30c7\u30b6\u30a4\u30f3\u306e\u30a4\u30d9\u30f3\u30c8\u306b\u95a2\u4fc2\u3057\u3001\u77e9\u5f62\u95a2\u6570\u306e\u91cd\u307f\u306f\u4e00\u822c\u7684\u306b\u306f\u5747\u4e00\u3067\u3042\u308b\uff0e\u672c\u767a\u8868\u3067\u306f\uff0cHRF\u306e\u30d1\u30e9\u30e1\u30fc\u30bf\u3068\u77e9\u5f62\u95a2\u6570\u306e\u91cd\u307f\u3092\uff0c\u5404\u89b3\u6e2c\u30c7\u30fc\u30bf\u306b\u6700\u3082\u985e\u4f3c\u3059\u308b\u3088\u3046\u306b\u6700\u9069\u5316\u3059\u308badaptive HRF\u6cd5\u306e\u9069\u7528\u3092\u691c\u8a0e\u3059\u308b\uff0e<br \/>\n[\u65b9\u6cd5]<br \/>\n\u5bfe\u8c61\u3068\u3059\u308b\u30bf\u30b9\u30af\u306f\u3001N\u30d0\u30c3\u30af\u30bf\u30b9\u30af\u3067\u3042\u308b\uff0eN=2\u304a\u3088\u3073N=3\u306e\u5834\u5408\u306b\u3064\u3044\u3066\u691c\u8a0e\u3057\u305f\uff0eHRF\u306e\u30d1\u30e9\u30e1\u30fc\u30bf\u3068\u77e9\u5f62\u95a2\u6570\u306e\u91cd\u307f\u306f\uff0c\u57fa\u5e95\u95a2\u6570\u3068\u5b9f\u9a13\u30c7\u30fc\u30bf\u3068\u306e\u5dee\u3092\u6700\u5c0f\u5316\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u6c42\u3081\u3089\u308c\u308b\uff0e\u3053\u306e\u64cd\u4f5c\u306f\u5168\u3066\u306e\u88ab\u9a13\u8005\u306e\u5168\u3066\u306e\u30c1\u30e3\u30cd\u30eb\u306b\u5bfe\u3057\u3066\u884c\u3063\u305f\uff0e\u3057\u305f\u304c\u3063\u3066\u3001\u6700\u9069HRF\u306e\u30d1\u30e9\u30e1\u30fc\u30bf\u3068\u77e9\u5f62\u95a2\u6570\u306e\u91cd\u307f\u306f\u3059\u3079\u3066\u306e\u88ab\u9a13\u8005\u306e\u30c1\u30e3\u30f3\u30cd\u30eb\u3067\u6c7a\u5b9a\u3055\u308c\u305f\uff0e\u76ee\u7684\u95a2\u6570\u306f\uff0c\u56de\u5e30\u4fc2\u6570\u03b2\u304a\u3088\u3073\u6b8b\u7559\u8aa4\u5deee\u3092\u7528\u3044\u3066\u5c0e\u51fa\u3055\u308c\u305ft\u5024\u3067\u3042\u308b\uff0et\u5024\u3092\u6700\u5927\u5316\u3059\u308b\u305f\u3081\u306b\u30013\u3064\u306eHRF\u306e\u30d1\u30e9\u30e1\u30fc\u30bf\u304a\u3088\u3073\u77e9\u5f62\u95a2\u6570\u306e\u91cd\u307f\u3092\u6c7a\u5b9a\u3057\u305f\uff0eadaptive HRF\u304a\u3088\u3073\u901a\u5e38\u306eHRF\u3092\u4f7f\u7528\u3057\u305f\u969b\u306e\u6d3b\u6027\u30c1\u30e3\u30f3\u30cd\u30eb\u3092\u6bd4\u8f03\u3059\u308b\u3053\u3068\u3067\u3001\u624b\u6cd5\u306e\u6709\u52b9\u6027\u306b\u3064\u3044\u3066\u691c\u8a0e\u3092\u884c\u3063\u305f\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<ul>\n<li>\u8cea\u7591\u5fdc\u7b54<\/li>\n<\/ul>\n<p>\u4eca\u56de\u306e\u8b1b\u6f14\u767a\u8868\u3067\u306f\uff0c\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u8cea\u7591\u3092\u53d7\u3051\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<br \/>\n<strong>\u30fb\u8cea\u554f\u5185\u5bb9<\/strong><strong>1<\/strong><br \/>\n\u540d\u53e4\u5c4b\u5927\u5b66\u306e\u65b9\u304b\u3089\u8cea\u554f\u3092\u3044\u305f\u3060\u304d\u307e\u3057\u305f\uff0e\u3053\u3061\u3089\u306e\u8cea\u554f\u306f\u7573\u307f\u8fbc\u307f\u3092\u884c\u3063\u3066\u3044\u308b\u3068\u8a00\u3053\u3068\u3067\u3057\u305f\u304c\uff0c\u7573\u307f\u8fbc\u307f\u3068\u306f\u3069\u3046\u3044\u3046\u51e6\u7406\u3092\u884c\u3063\u3066\u3044\u308b\u306e\u304b\u3068\u3044\u3046\u3082\u306e\u3067\u3057\u305f\uff0e\u3053\u306e\u8cea\u554f\u306b\u5bfe\u3059\u308b\u79c1\u306e\u56de\u7b54\u306f\uff0c\u7573\u307f\u8fbc\u307f\u306f\u30a4\u30e1\u30fc\u30b8\u3067\u306f\u8db3\u3057\u7b97\u306e\u3088\u3046\u306a\u3082\u306e\u3067\uff0c\u8a08\u7b97\u5024\u304c\u524d\u306e\u6570\u5024\u306e\u5f71\u97ff\u3092\u53d7\u3051\u308b\u3082\u306e\u3067\u3042\u308b\u3068\u3044\u3046\u8aac\u660e\u3068\u3068\u3082\u306b\uff0c\u3069\u306e\u3088\u3046\u306b\u51e6\u7406\u3057\u3066\u3044\u308b\u306e\u304b\u3092\u5177\u4f53\u7684\u306a\u6570\u5024\u3092\u7528\u3044\u3066\u8aac\u660e\u3057\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<br \/>\n<strong>\u30fb\u8cea\u554f\u5185\u5bb9<\/strong><strong>2<\/strong><br \/>\n\u591a\u304f\u306e\u65b9\u304b\u3089\u306e\u8cea\u554f\u3067\uff0c\u3053\u306e\u6280\u8853\u304c\u3067\u304d\u308b\u3053\u3068\u306b\u3088\u308a\u4f55\u304c\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308b\u306e\u304b\u3068\u3044\u3046\u8cea\u554f\u3092\u3044\u305f\u3060\u304d\u307e\u3057\u305f\uff0e\u3053\u306e\u8cea\u554f\u306b\u5bfe\u3059\u308b\u56de\u7b54\u3067\u3059\u304c\uff0c\u666e\u6bb5\u884c\u3063\u3066\u3044\u308b\u89e3\u6790\u3067\u306f\u3059\u3079\u3066\u306e\u8133\u90e8\u4f4d\u3067\u540c\u4e00\u306e\u8840\u6d41\u5909\u5316\u30e2\u30c7\u30eb\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u304c\uff0c\u5b9f\u969b\u306e\u8133\u8840\u6d41\u306f\u3069\u306e\u90e8\u4f4d\u3082\u540c\u3058\u3082\u306e\u3067\u306f\u306a\u3044\uff0e\u305d\u3053\u3067\uff0c\u8840\u6d41\u3092\u6b63\u78ba\u306b\u8868\u308f\u3057\u305f\u30e2\u30c7\u30eb\u3092\u4f5c\u6210\u3059\u308b\u3053\u3068\u3067\uff0c\u8840\u6d41\u304c\u3069\u306e\u30bf\u30a4\u30df\u30f3\u30b0\uff0c\u3069\u306e\u3088\u3046\u306a\u5927\u304d\u3055\u3067\u767a\u751f\u3057\u3066\u3044\u308b\u306e\u304b\uff0c\u304c\u308f\u304b\u308a\uff0c\u5448\u793a\u523a\u6fc0\u306b\u5bfe\u3059\u308b\u51e6\u7406\u304c\u8133\u5185\u3067\u3069\u306e\u3088\u3046\u306b\u884c\u308f\u308c\u3066\u3044\u308b\u306e\u304b\u3092\u5b9a\u91cf\u7684\u306b\u6c42\u3081\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3068\u8aac\u660e\u3057\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<ul>\n<li>\u611f\u60f3<\/li>\n<\/ul>\n<p>\u4eca\u56de\u306e\u767a\u8868\u3067\u306f\uff0c\u7d50\u679c\u304c\u76f4\u524d\u306b\u51fa\u305f\u305f\u3081\u5341\u5206\u306a\u8003\u5bdf\u304c\u3067\u304d\u3066\u304a\u3089\u305a\uff0c\u79c1\u81ea\u8eab\u304c\u3042\u307e\u308a\u7406\u89e3\u3067\u304d\u3066\u3044\u306a\u3044\u3068\u3053\u308d\u3082\u3042\u308a\u307e\u3057\u305f\uff0e\u3057\u304b\u3057\uff0c\u8a71\u3092\u3057\u3066\u3044\u305f\u3060\u3044\u305f\u4e2d\u3067\u3053\u306e\u65b9\u6cd5\u304c\u3069\u306e\u3088\u3046\u306a\u3053\u3068\u306b\u5f79\u7acb\u3064\u306e\u304b\uff0c\u3069\u3046\u3059\u308c\u3070\u3055\u3089\u306b\u826f\u304f\u306a\u308b\u306e\u304b\u306a\u3069\uff0c\u69d8\u3005\u306a\u3053\u3068\u306f\u8a71\u3057\u5408\u3046\u3053\u3068\u304c\u3067\u304d\u3068\u3066\u3082\u8cb4\u91cd\u306a\u4f53\u9a13\u3060\u3063\u305f\u3068\u601d\u3044\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<ol start=\"3\">\n<li>\u8074\u8b1b<\/li>\n<\/ol>\n<p>\u4eca\u56de\u306e\u8b1b\u6f14\u4f1a\u3067\u306f\uff0c\u4e0b\u8a18\u306e7\u4ef6\u306e\u767a\u8868\u3092\u8074\u8b1b\u3057\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"529\">\u767a\u8868\u30bf\u30a4\u30c8\u30eb\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a\u3000fNIRS\u3067\u8a55\u4fa1\u3059\u308b\u5b66\u7fd2\u306b\u3088\u308b\u8133\u306e\u53ef\u5851\u7684\u5909\u5316<br \/>\n\u8457\u8005\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u7686\u5ddd\u3000\u6cf0\u4ee3<br \/>\n\u30bb\u30c3\u30b7\u30e7\u30f3\u540d\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u5927\u4f1a\u9577\u8b1b\u6f14<br \/>\nAbstruct\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u5150\u7ae5\u671f\u304b\u3089\u9752\u5e74\u671f\u305d\u3057\u3066\u6210\u4eba\u671f\u306b\u3044\u305f\u308b\u307e\u3067\u306b\u8a8d\u77e5\u6a5f\u80fd\u306f\u767a\u9054\u3057\uff0c\u305d\u308c\u306b\u4f34\u3063\u3066\u5927\u8133\u306e\u69cb\u9020\u3084\u6a5f\u80fd\u3082\u5927\u304d\u304f\u5909\u5316\u3059\u308b\uff0e\u8a00\u8a9e\u5b66\u7fd2(\u7fd2\u5f97)\u306e\u81e8\u754c\u671f\u3068\u3044\u3046\u8a00\u8449\u304c\u793a\u3059\u3068\u304a\u308a\uff0c\u8a00\u8a9e\u306e\u5b66\u7fd2\u3068\u3044\u3046\u8a8d\u77e5\u6a5f\u80fd\u3092\u4f8b\u306b\u3068\u3063\u3066\u3082\u305d\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306f\u5e74\u9f62\u3068\u3068\u3082\u306b\u5287\u7684\u306b\u5909\u5316\u3059\u308b\u304c\uff0c\u305d\u306e\u5b66\u7fd2\u6a5f\u69cb\u306b\u95a2\u4e0e\u3059\u308b\u8133\u6a5f\u69cb\u306e\u767a\u9054\u5909\u5316\u306b\u3064\u3044\u3066\u306f\u591a\u304f\u306f\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u306a\u3044\uff0e\u3053\u308c\u306f\u767a\u9054\u671f\u306e\u8133\u3092\u691c\u8a0e\u3059\u308b\u624b\u6cd5\u306b\u69d8\u3005\u306a\u5236\u7d04\u304c\u3042\u3063\u305f\u3053\u3068\u306b\u3082\u3088\u308b\u3068\u601d\u308f\u308c\u308b\uff0e\u672c\u8b1b\u6f14\u3067\u306f\u767a\u9054\u8133\u3092\u6bd4\u8f03\u7684\u7c21\u4fbf\u306b\u8a08\u6e2c\u3067\u304d\u308bfNIRS(functional Near Infrared Spectroscopy)\u3092\u7528\u3044\u3066\uff0c\u767a\u9054\u671f\u306e\u5b66\u7fd2\u6a5f\u69cb\u306b\u95a2\u4e0e\u3059\u308b\u8133\u5185\u6a5f\u69cb\u3092\u691c\u8a0e\u3057\u305f\u4e00\u9023\u306e\u7814\u7a76\u306b\u3064\u3044\u3066\u6982\u8aac\u3059\u308b\uff0e\u65b0\u751f\u5150\u671f\uff0c\u5b66\u7ae5\u671f\uff0c\u601d\u6625\u671f\uff0c\u524d\u6210\u4eba\u671f\u306e\u5404\u767a\u9054\u30b9\u30c6\u30fc\u30b8\u306b\u304a\u3044\u3066\uff0c\u5b66\u7fd2\u306b\u3068\u3082\u306a\u3063\u3066\u3069\u306e\u3088\u3046\u306b\u8133\u5185\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u304c\u518d\u7de8\u6210\u3055\u308c\u308b\u304b\u3092\u6982\u89b3\u3057\uff0c\u767a\u9054\u306b\u3088\u308b\u8133\u306e\u53ef\u5851\u6027\u306e\u5909\u5316\u306b\u3064\u3044\u3066\u8003\u5bdf\u3059\u308b\uff0e\u4ee5\u4e0b\u306b\u5404\u7814\u4fee\u306e\u6982\u8981\u306b\u3064\u3044\u3066\u793a\u3059\uff0e<br \/>\n\u7814\u7a761\u3067\u306f\u5b66\u7ae5\u671f(9-12\u6b73)\uff0c\u601d\u6625\u671f(13-16)\uff0c\u6210\u4eba\u671f(18-21\u6b73)\u306e\u97f3\u97fb\u5b66\u7fd2\u524d\u5f8c\u306e\u8133\u6a5f\u80fd\u306e\u5909\u5316\uff0c\u7814\u7a762\u3067\u306f\u540c\u3058\u5e74\u9f62\u306e3\u7fa4\u3092\u5bfe\u8c61\u3068\u3057\u3066\u63a8\u8ad6\u5b66\u7fd2\u524d\u5f8c\u306e\u8133\u6a5f\u80fd\u306e\u5909\u5316\u3092\u691c\u8a0e\u3057\u305f\uff0e\u5b9f\u9a13\u53c2\u52a0\u8005\u306f\u7814\u7a761\u3067\u306f\uff0c\u82f1\u8a9e\u97f3\u97fb\/r\/\uff0c\/l\/\u306e\u97f3\u97fb\u306e\u540c\u5b9a\u3084\u5f01\u5225\u306b\u3064\u3044\u3066\u7d041\u30f6\u6708\u9593\u96fb\u5b50\u8f9e\u66f8\u5185\u306e\u30a2\u30d7\u30ea\u306b\u3088\u308b\u5b66\u7fd2\u3092\u884c\u3044\uff0c\u5b9f\u9a132\u3067\u306fi-pod\u4e0a\u306e\u30a2\u30d7\u30ea\u306b\u3088\u308a\u5358\u8a9e\u306e\u6bcd\u97f3\uff0c\u5b50\u97f3\u69cb\u9020\u306b\u3064\u3044\u3066\u306e\u63a8\u8ad6\u5b66\u7fd2\u3092\u7d04\u30ab\u6708\u9593\u884c\u3063\u305f\uff0e\u305d\u306e\u5b66\u7fd2\u524d\u5f8c\u306b\u304a\u3044\u3066\u97f3\u97fb\u540c\u5b9a\u3084\u63a8\u8ad6\u306e\u30bf\u30b9\u30af\u3092\u305d\u308c\u305e\u308c\u884c\u3063\u3066\u3044\u308b\u9593\u306e\u8133\u6d3b\u52d5\u8a08\u6e2c\u3084\u884c\u52d5\u5b9f\u9a13\u3092\u884c\u3044\uff0c\u8133\u6d3b\u52d5\u3084\u8133\u6a5f\u80fd\u7d50\u5408\u306e\u5909\u5316\uff0c\u884c\u52d5\u3068\u8133\u53cd\u5fdc\u306e\u95a2\u9023\u3092\u691c\u8a0e\u3057\u305f\uff0e\u7814\u7a763\u3067\u306f\u65b0\u751f\u5150\u3092\u5bfe\u8c61\u3068\u3057\u3066\/r\/\u304b\u3089\/l\/\u306b\u5f90\u3005\u306b\u5909\u5316\u3059\u308b\/right\/-\/light\/\u7cfb\u5217\u523a\u6fc0\u3092\u7528\u3044\u305f\u7d71\u8a08\u5b66\u7fd2\u523a\u6fc0\u3092\u63d0\u793a\u3057\uff0c\u305d\u306e\u524d\u5f8c\u306e\u308c\u30b9\u30c6\u30a3\u30f3\u30b0\u72b6\u614b(\u5b89\u9759\u72b6\u614b)\u306e\u8133\u6a5f\u80fd\u7d50\u5408\u306e\u5909\u5316\u304a\u3088\u3073\u97f3\u97fb\u5f01\u5225\u306e\u8133\u53cd\u5fdc\u3092\u691c\u8a0e\u3057\u305f\uff0e\u3053\u308c\u3089\u306e\u7d50\u679c\uff0c\u5e74\u9f62\u7fa4\u5225\u306b\u5b66\u7fd2\u306b\u95a2\u9023\u3057\u305f\u7570\u306a\u308b\u8133\u5185\u6a5f\u69cb\u306e\u5909\u5316\uff0c\u7279\u306b\u5b66\u7fd2\u52b9\u679c\u306b\u3068\u3082\u306a\u3046\u8133\u6a5f\u80fd\u7d50\u5408\u306e\u5909\u5316\u304c\u307f\u3089\u308c\u305f\uff0e<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u3053\u306e\u767a\u8868\u306f\u5150\u7ae5\u671f\u304b\u3089\u9752\u5e74\u671f\uff0c\u6210\u4eba\u671f\u3067\u306f\uff0c\u8133\u306e\u8a8d\u77e5\u6a5f\u80fd\u306f\u5927\u304d\u304f\u7570\u306a\u308b\u305f\u3081\uff0c\u3059\u3079\u3066\u306e\u6642\u671f\u3067\uff0cfNIRS\u3092\u7528\u3044\u3066\u8133\u6a5f\u80fd\u306e\u5909\u5316\u3092\u8ffd\u3063\u305f\u3082\u306e\u3067\u3057\u305f\uff0e\u3053\u306e\u7814\u7a76\u3067\u306f\uff0c\u6210\u4eba\u671f\u3068\u5b66\u7ae5\u671f\u3067\u306f\u540c\u3058\u8ab2\u984c\u3067\u3082\u51e6\u7406\u90e8\u4f4d\u304c\u7570\u306a\u308b\u3053\u3068\uff0c\u5b66\u7fd2\u52b9\u679c\u306b\u4f34\u3046\u8133\u6a5f\u80fd\u7d50\u5408\u306e\u5909\u5316\u304c\u898b\u3089\u308c\u305f\u3053\u3068\u304c\u5206\u304b\u3063\u305f\u3068\u3042\u308a\u307e\u3057\u305f\uff0e\u3053\u306e\u767a\u8868\u306b\u3088\u308a\uff0c\u81ea\u5206\u304c\u7814\u7a76\u3092\u884c\u3046\u969b\u306b\u3082\u5b66\u7fd2\u52b9\u679c\u306b\u3064\u3044\u3066\u306e\u8003\u5bdf\u304c\u91cd\u8981\u3067\u3042\u308b\u3068\u6539\u3081\u3066\u611f\u3058\u308b\u5185\u5bb9\u3067\u3057\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"529\">\u767a\u8868\u30bf\u30a4\u30c8\u30eb\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1aConcurrent near infrared spectroscopy (fNIRS) and functional MRI studies on human brain function and physiology.<br \/>\n\u8457\u8005\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a Yunjie Tong<br \/>\n\u30bb\u30c3\u30b7\u30e7\u30f3\u540d\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u7279\u5225\u8b1b\u6f14<br \/>\nAbstruct\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a Functional MRI(fMRI) and near infrared spectroscopy (NIRS) are two noninvasive imaging modalities commonly used to study human brain function. However, they can only measure neuronal activation indirectly through neurovascular coupling. Other non-neuronal physiological fluctuations, such as respiration, can also influence their signals. In thin talk, I will introduce a novel method which identifies a physiological low frequency oscillation(LFO) in fMRI signals through concurrent fMRI\/NIRS study. We have demonstrated that this LFO is a dynamic signal which travels with the blood throughout the brain. Moreover, we found that the same LFO in the periphery. These findings indicated the systemic feature of this wave and its potential extracerebral origin. To put our discoveries into practical application, we have designed methods to convert this \u201cconfounding\u201d systemic signal into a useful perfusion biomarker. For examples, using the LFO and its temporal shifts, dynamic cerebral blood flow map has been obtained from regular resting state fMRI scans, which allows simultaneous assessment of functional networks and perfusion. Furthermore, novel methods have been developed based on the same analytical principle to: 1) track cardiac pulsation wave in the fMRI data; 2) denoise fMRI data and 3) assess serebral blood flow recovery in Moyamoya patients after surgery.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u3053\u306e\u767a\u8868\u3067\u7740\u76ee\u3057\u305f\u306e\u306f\u8a08\u6e2c\u30c7\u30fc\u30bf\u3092\u6570\u79d2\u305a\u3064\u305a\u3089\u3057\u3066\u76f8\u95a2\u3092\u3068\u308b\u624b\u6cd5\u3067\u3057\u305f\uff0e\u3053\u308c\u306f\u5f93\u6765\u3042\u307e\u308a\u898b\u304b\u3051\u306a\u3044\u65b9\u6cd5\u3067\u3042\u308a\uff0c\u8208\u5473\u3092\u60f9\u304b\u308c\u308b\u5185\u5bb9\u3067\u3057\u305f\uff0e\u3053\u306e\u65b9\u6cd5\u3092\u7528\u3044\u308b\u3053\u3068\u306b\u3088\u308a\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3092\u898b\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u8003\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"529\">\u767a\u8868\u30bf\u30a4\u30c8\u30eb\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a\u3000\u5149\u8a08\u6e2c\u306b\u3088\u308a\u53ef\u8996\u5316\u3059\u308b\u767a\u9054\u8133\u306e\u6a5f\u80fd\u7684\u30cd\u30c3\u30c8\u30ef\u30fc\u30af<br \/>\n\u8457\u8005\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u4fdd\u524d\u3000\u6587\u9ad8<br \/>\n\u30bb\u30c3\u30b7\u30e7\u30f3\u540d\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u62db\u5f85\u8b1b\u6f14<br \/>\nAbstruct\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u8133\u8840\u6db2\u306e\u5c40\u6240\u7684\u306a\u9178\u7d20\u5316\u72b6\u614b\u306e\u5909\u5316\u3092\u6307\u6a19\u3068\u3057\u3066\u8133\u306e\u6d3b\u52d5\u3092\u3068\u3089\u3048\u308b\u3053\u3068\u3067\uff0c\u8133\u306b\u304a\u3051\u308b\u5c40\u5728\u5316\u3057\u305f\u6a5f\u80fd\u304c\u660e\u3089\u304b\u306b\u3055\u308c\u3066\u304d\u305f\uff0e\u307e\u305f\uff0c\u8fd1\u5e74\u306f\uff0c\u7814\u7a76\u53c2\u52a0\u8005\u306e\u96c6\u56e3\u5185\u3067\u5c40\u6240\u7684\u306a\u4fe1\u53f7\u5909\u5316\u91cf\u3068\u884c\u52d5\u6307\u6a19\u3068\u306e\u76f8\u95a2\u95a2\u4fc2\u304c\u691c\u8a0e\u3055\u308c\u308b\u306a\u3069\uff0c\u8133\u6a5f\u80fd\u8a08\u6e2c\u3068\u884c\u52d5\u8a08\u6e2c\u3068\u304c\u65b0\u305f\u306a\u878d\u5408\u3092\u679c\u305f\u3057\u3066\u3044\u308b\uff0e\u76ae\u8cea\u6d3b\u52d5\u306b\u4f34\u3046\u4fe1\u53f7\u5909\u5316\u306f\u5c40\u6240\u7684\u306a\u51e6\u7406\u3092\u5909\u66f4\u3059\u308b\u304c\u6545\u306b\uff0c\u8907\u6570\u306e\u76ae\u8cea\u9818\u57df\u306e\u4fe1\u53f7\u5909\u5316\u3092\u540c\u6642\u306b\u3068\u3089\u3048\u308b\u3053\u3068\u306b\u3088\u3063\u3066\uff0c\u9818\u57df\u9593\u306e\u95a2\u4fc2\u6027\u3092\u63a8\u6e2c\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308b\uff0eBiswal\u3089(1995)\u304c\u6a5f\u80fd\u7684\u78c1\u6c17\u5171\u9cf4\u753b\u50cf\u6cd5(fMRI)\u306eBOLD\u4fe1\u53f7\u3067\u5de6\u53f3\u534a\u7403\u306e\u904b\u52d5\u91ce\u306b\u304a\u3051\u308b\u81ea\u767a\u6d3b\u52d5\u3092\u3068\u3089\u3048\u3066\u305d\u306e\u9593\u306e\u540c\u671f\u751f\u3092\u793a\u3057\u3066\u4ee5\u6765\uff0c20\u5e74\u4f59\u308a\u306e\u9593\u306b\u81a8\u5927\u306a\u91cf\u306e\u77e5\u898b\u304c\u84c4\u7a4d\u3055\u308c\uff0c\u57fa\u790e\u7814\u7a76\u306e\u307f\u306a\u3089\u305a\u81e8\u5e8a\u7684\u306a\u5fdc\u7528\u306b\u307e\u3067\u5411\u304b\u3063\u3066\u3044\u308b\uff0e\u4fe1\u53f7\u5909\u5316\u306e\u540c\u671f\u751f\u306b\u3088\u3063\u3066\u5b9a\u7fa9\u308f\u308c\u308b\u9818\u57df\u9593\u306e\u95a2\u4fc2\u306f\u6a5f\u80fd\u7684\u7d50\u5408\u3068\u547c\u3070\u308c\u308b\u304c\uff0c\u6a5f\u80fd\u7684\u7d50\u5408\u306e\u96c6\u5408\u3067\u3042\u308b\u8133\u6a5f\u80fd\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3068\u3068\u3082\u306b\u9818\u57df\u9593\u306e\u89e3\u5256\u5b66\u7684\u306a\u6295\u5c04\u3068\u6a5f\u80fd\u7684\u306a\u9023\u95a2\u306e\u3044\u305a\u308c\u304b\uff0c\u3082\u3057\u304f\u306f\uff0c\u4e21\u65b9\u3092\u53cd\u6620\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u308b\uff0e\u8133\u304c\u69cb\u9020\u3068\u6a5f\u80fd\u306e\u4e21\u9762\u3067\u5f62\u6210\u3055\u308c\u308b\u904e\u7a0b\u306b\u3042\u308b\u4e73\u5150\u671f\u3067\u306f\uff0c\u6a5f\u80fd\u7684\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3092\u53ef\u8996\u5316\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u306b\u306a\u308b\u3068\u8003\u3048\u3089\u308c\uff0cfMRI\u3092\u7528\u3044\u305f\u3044\u304f\u3064\u304b\u306e\u7814\u7a76\u3067\u306f\u6210\u4eba\u306e\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306b\u985e\u3057\u305f\u30d1\u30bf\u30fc\u30f3\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u308b\uff0e\u3057\u304b\u3057\u306a\u304c\u3089\uff0c\u4e3b\u3068\u3057\u3066\u7761\u7720\u6642\u306e\u81ea\u767a\u6d3b\u52d5\u306b\u57fa\u3065\u3044\u305f\u6a5f\u80fd\u7684\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u63a2\u7d22\u306b\u4f9d\u5b58\u3057\u3066\u3044\u308b\u3053\u3068\u3082\u3042\u308a\uff0c\u4e73\u5150\u671f\u306e\u7279\u5fb4\u7684\u306b\u8d77\u3053\u308b\u3068\u60f3\u5b9a\u3055\u308c\u308b\u6a5f\u80fd\u306e\u5c40\u5728\u5316\u3068\u9818\u57df\u9593\u3092\u67b6\u3059\u308b\u5927\u57df\u5316\u306e\u53cc\u65b9\u5411\u306b\u5411\u304b\u3046\u767a\u9054\u306b\u3064\u3044\u3066\u306f\u9650\u5b9a\u7684\u306a\u60c5\u5831\u3092\u5f97\u308b\u306b\u7559\u307e\u3063\u3066\u3044\u308b\uff0e\u591a\u30c1\u30e3\u30f3\u30cd\u30eb\u306e\u8fd1\u8d64\u5916\u5149\u8133\u6a5f\u80fd\u8a08\u6e2c\u88c5\u7f6e(NIRS)\u3092\u7528\u3044\u308b\u3053\u3068\u306b\u3088\u3063\u3066\uff0c\u4e73\u5150\u306e\u81ea\u767a\u6d3b\u52d5\u3060\u3051\u3067\u306a\u304f\u97f3\u58f0\u523a\u6fc0\u306b\u5bfe\u3059\u308b\u5fdc\u7b54\u3092\u5e83\u3044\u76ae\u8cea\u9818\u57df\u3067\u540c\u6642\u306b\u8a08\u6e2c\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3042\u308b\u305f\u3081\uff0c\u4e0a\u8a18\u306e\u767a\u9054\u904e\u7a0b\u306b\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308b\uff0e\u672c\u8b1b\u6f14\u3067\u306f\uff0c\u4e73\u5150\u3092\u5bfe\u8c61\u3068\u3057\u305fNIRS\u8a08\u6e2c\u306e\u7d50\u679c\u3092\u3082\u3068\u306b\u3057\u3066\uff0c\u81ea\u767a\u6d3b\u52d5\u3067\u89b3\u6e2c\u3055\u308c\u308b\u3088\u3046\u306a\u57fa\u5e79\u3068\u306a\u308b\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u304c\u5f62\u6210\u3055\u308c\u308b\u3068\u3044\u3046\u4eee\u8aac\u3092\u63d0\u6848\u3059\u308b\uff0e\u307e\u305f\uff0c\u6a5f\u80fd\u7684\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3067\u4e2d\u5fc3\u7684\u306a\u5f79\u5272\u3092\u679c\u305f\u3059(\u30cf\u30d6)\u9818\u57df\u3092\u540c\u5b9a\u3059\u308b\u3053\u3068\u306b\u3088\u308a\uff0c\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3092\u691c\u8a0e\u3059\u308b\u3053\u3068\u304c\u304b\u3048\u3063\u3066\u5c40\u5728\u6027\u3092\u9855\u5728\u5316\u3055\u305b\u308b\u3053\u3068\u306b\u3082\u6ce8\u76ee\u3059\u308b\uff0e\u3053\u306e\u3088\u3046\u306a\u4e2d\u5fc3\u6027\u306e\u9ad8\u3044\u9818\u57df\u304c\u3069\u306e\u9818\u57df\u3068\u6a5f\u80fd\u7684\u7d50\u5408\u3092\u6709\u3059\u308b\u304b\u306b\u3064\u3044\u3066\u306f\uff0c\u4e73\u5150\u306e\u767a\u9054\u904e\u7a0b\u306b\u304a\u3051\u308b\u300c\u500b\u6027\u300d\u304c\u3042\u3089\u308f\u308c\u308b\u3068\u3044\u3046\u53ef\u80fd\u6027\u306b\u3064\u3044\u3066\u3082\u8b70\u8ad6\u3059\u308b\uff0e<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u3053\u306e\u767a\u8868\u3067\u306f\uff0c\u4e73\u5150\u671f\u306b\u304a\u3044\u3066\u91cd\u8981\u3067\u3042\u308b\u6a5f\u80fd\u7684\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u53ef\u8996\u5316\u306e\u7814\u7a76\u3092\u884c\u3063\u3066\u3044\u308b\uff0e\u5f93\u6765\u306e\u65b9\u6cd5\u3068\u306f\u7570\u306a\u308a\uff0c\u6a5f\u80fd\u7684\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3067\u4e2d\u5fc3\u7684\u306a\u5f79\u5272\u3092\u679c\u305f\u3059\u9818\u57df\u3092\u540c\u5b9a\u3057\uff0c\u30b3\u30cd\u30af\u30c6\u30a3\u30d3\u30c6\u30a3\u3092\u691c\u8a0e\u3059\u308b\u3053\u3068\u3067\u8133\u90e8\u4f4d\u3054\u3068\u306e\u7279\u5fb4\u3092\u898b\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\uff0c\u8208\u5473\u3092\u6301\u3061\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"529\">\u767a\u8868\u30bf\u30a4\u30c8\u30eb\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a NIRS\u3092\u7528\u3044\u305f\u55c5\u899a\u6a5f\u80fd\u306e\u691c\u8a0e<br \/>\n\u8457\u8005\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u76f4\u4e95\u3000\u671b<br \/>\n\u30bb\u30c3\u30b7\u30e7\u30f3\u540d\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u30b7\u30f3\u30dd\u30b8\u30a6\u30e0<br \/>\nAbstruct\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u8fd1\u5e74\uff0c\u8074\u899a\uff0c\u8996\u899a\uff0c\u89e6\u899a\u306a\u3069\u306e\u611f\u899a\u6a5f\u80fd\u306b\u3064\u3044\u3066\uff0cfunctional Near-Infrared Spectroscopy(fNIRS)\u3092\u7528\u3044\u305f\u7814\u7a76\u306e\u77e5\u898b\u304c\u84c4\u7a4d\u3055\u308c\u3066\u304d\u3066\u3044\u308b\u304c\uff0c\u8074\u899a\u6a5f\u80fd\u306e\u691c\u8a0e\u306f\u5c11\u306a\u3044\uff0e\u55c5\u899a\u6a5f\u80fd\u306e\u8133\u306f\uff0c\u9999\u6599\u3092\u6301\u7d9a\u7684\u306b\u5448\u793a\u3059\u308b\u65b9\u6cd5\u304c\u591a\u304f\u7528\u3044\u3089\u308c\uff0c\u523a\u6fc0\u5448\u793a\u306e\u6642\u9593\u7d71\u5236\u304c\u56f0\u96e3\u3067\u3042\u308b\u3060\u3051\u3067\u306a\u304f\uff0c\u55c5\u899a\u304c\u9806\u5fdc\u3057\u3066\u9999\u308a\u3092\u77e5\u899a\u3057\u306a\u304f\u306a\u308b\u3068\u3044\u3046\u554f\u984c\u3084\uff0c\u8a08\u5104\u3059\u308b\u7a7a\u9593\u306b\u9999\u6599\u304c\u6b8b\u7559\u3057\u3066\u3057\u307e\u3046\u6b8b\u308a\u9999\u306e\u554f\u984c\u304c\u3042\u3063\u305f\uff0e\u305d\u3053\u3063\u3067\uff0c\u9999\u6599\u3092\u96e2\u6563\u7684\u306b\u30d1\u30eb\u30b9\u5c04\u51fa\u3059\u308b\u65b9\u6cd5\u3092\u7528\u3044\u305f\u300c\u9999\u308a\u767a\u751f\u30c7\u30d0\u30a4\u30b9\u300d(Furukawa, Suzuki, &amp; Okada, 2013)\u3092\u7528\u3044\u3066\uff0c\u55c5\u899a\u523a\u6fc0\u6642\u306e\u524d\u982d\u90e8\u306e\u8133\u6d3b\u52d5\u3092\uff0cfNIRS\u3092\u7528\u3044\u3066\u6e2c\u5b9a\u3057\u305f\uff0e\u672c\u767a\u8868\u3067\u306f\uff0cfNIRS\u3092\u7528\u3044\u305f\u55c5\u899a\u6a5f\u80fd\u8a08\u6e2c\u306e\u53ef\u80fd\u6027\u3068\u554f\u984c\u70b9\u306b\u3064\u3044\u3066\u8b70\u8ad6\u3057\u305f\u3044\uff0e<br \/>\n\u3055\u3089\u306b\uff0c\u55c5\u899a\u6a5f\u80fd\u3068\u767a\u9054\u969c\u5bb3\u3068\u306e\u95a2\u9023\u306b\u3064\u3044\u3066\u3082\u691c\u8a0e\u3092\u884c\u3063\u305f\uff0e\u81ea\u9589\u75c7\u30b9\u30da\u30af\u30c8\u30e9\u30e0\u969c\u5bb3(Autism Spectrum Disorders, ASD)\u306f\uff0c\u793e\u4f1a\u7684\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u306b\u56f0\u96e3\u3092\u793a\u3057\uff0c\u9650\u5b9a\u3055\u308c\u305f\u8208\u5473\u3068\u53cd\u5fa9\u7684\u306a\u884c\u52d5\u3092\u793a\u3059\u3053\u3068\u3067\u8a3a\u65ad\u3055\u308c\u308b\u767a\u9054\u969c\u5bb3\u3067\u3042\u308b\uff0eASD\u3068\u611f\u899a\u7570\u5e38\u3068\u306e\u95a2\u9023\u306f\u591a\u304f\u5831\u544a\u3055\u308c\u3066\u304a\u308a\uff0cASD\u5150\u30fb\u8005\u306b\u304a\u3051\u308b\u55c5\u899a\u306e\u611f\u899a\u7570\u5e38(\u611f\u899a\u904e\u654f sensory hypersensitivity\u3000\u304a\u3088\u3073\u611f\u899a\u9ebb\u75fa sensory hyposensitivity)\u306f\uff0c50%\u4ee5\u4e0a\u306b\u3082\u306e\u307c\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b(Lane et al., 2010; Schoen et al., 2009)\uff0e\u305d\u3053\u3067\uff0cASD\u5150\u30fb\u8005\u3092\u5bfe\u8c61\u306b\uff0c\u300c\u9999\u308a\u767a\u751f\u30c7\u30d0\u30a4\u30b9\u300d\u3092\u7528\u3044\u3066\u8a55\u4fa1\u3057\u305ffNIRS\u8a08\u6e2c\u3092\u884c\u3044\uff0c\u55c5\u899a\u523a\u6fc0\u3078\u306e\u691c\u77e5\u95be\u5024\u3068\u306e\u95a2\u9023\u304a\u3088\u3073\uff0c\u305d\u306e\u4ed6\u306e\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u3068\u306e\u95a2\u9023\u306e\u691c\u8a0e\u3092\u884c\u3063\u305f\u7814\u7a76\u306b\u3064\u3044\u3066\u7d39\u4ecb\u3057\u305f\u3044\uff0e<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u3053\u306e\u767a\u8868\u306f\uff0c\u4ed6\u306e\u611f\u899a\u6a5f\u80fd\u306b\u6bd4\u3079\u3066\u691c\u8a0e\u306e\u5c11\u306a\u3044\u55c5\u899a\u306e\u7814\u7a76\u306b\u3064\u3044\u3066\u3067\u3057\u305f\uff0e\u3053\u3053\u3067\u306f\uff0c\u55c5\u899a\u306b\u3064\u3044\u3066\u306e\u7814\u7a76\u3092\u884c\u3046\u4e0a\u3067\u306e\u554f\u984c\u3092\u89e3\u6c7a\u3059\u308b\u305f\u3081\u300c\u9999\u308a\u767a\u751f\u30c7\u30d0\u30a4\u30b9\u300d\u3092\u4f7f\u7528\u3057\u3066\u3044\u305f\uff0e\u307e\u305f\uff0c\u55c5\u899a\u6a5f\u80fd\u3068\u767a\u9054\u969c\u5bb3\u306e\u95a2\u9023\u306b\u3064\u3044\u3066\u3082\u767a\u8868\u3055\u308c\u3066\u3044\u305f\uff0e\u4eca\u307e\u3067\u3068\u306f\u8996\u70b9\u306e\u7570\u306a\u308b\u55c5\u899a\u306b\u6ce8\u76ee\u3057\u3066\u304a\u308a\uff0c\u3053\u308c\u304b\u3089\u306e\u7814\u7a76\u306e\u9032\u5c55\u304c\u6c17\u306b\u306a\u308b\u5185\u5bb9\u3060\u3063\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"529\">\u767a\u8868\u30bf\u30a4\u30c8\u30eb\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a NIRS\u3092\u7528\u3044\u305f\u767a\u9054\u969c\u5bb3\u306e\u8a3a\u65ad\u30fb\u6cbb\u7642\u52b9\u679c\u5224\u5b9a\u306e\u8a66\u307f<br \/>\n\u8457\u8005\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u9580\u7530\u3000\u884c\u53f2<br \/>\n\u30bb\u30c3\u30b7\u30e7\u30f3\u540d\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u30b7\u30f3\u30dd\u30b8\u30a6\u30e0<br \/>\nAbstruct\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u767a\u9054\u969c\u5bb3\u3067\u3042\u308b\u6ce8\u610f\u6b20\u5982\u30fb\u591a\u52d5\u6027\u969c\u5bb3(Attention Deficit Hyperactivity disorder; ADHD)\u306f\u5c0f\u5150\u65e9\u671f\u306b\u9069\u5207\u306a\u8a3a\u65ad\uff0c\u6cbb\u7642\u4ecb\u5165\u304c\u5fc5\u8981\u3067\u3042\u308b\u304c\uff0c\u75c5\u614b\u306b\u95a2\u4e0e\u3059\u308b\u5ba2\u89b3\u7684\u8a55\u4fa1\u6307\u6a19\u304c\u306a\u3044\u305f\u3081\u8a3a\u65ad\u30fb\u6cbb\u7642\u304c\u9045\u308c\u308b\u3053\u3068\u304c\u3042\u308b\uff0efMRI\u7b49\u306e\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u7814\u7a76\u304c\u9032\u307f\uff0cADHD\u306e\u75c5\u614b\u306b\u3064\u3044\u3066\u89e3\u660e\u3055\u308c\u3064\u3064\u3042\u308b\uff0e\u3057\u304b\u3057\u306a\u304c\u3089\uff0cADHD\u3068\u5b9a\u578b\u767a\u9054\u5150\u306e\u5f01\u5225\u304c\u53ef\u80fd\u3067\u304b\u3064\u81e8\u5e8a\u73fe\u5834\u3067\u5b9f\u7528\u5316\u3067\u304d\u308b\u6307\u6a19\u306f\u306a\u3044\uff0eADHD\u306e\u65e9\u671f\u8a3a\u65ad\u304a\u3088\u3073\u6cbb\u7642\u306b\u306f\uff0c\u85ac\u7269\u7642\u6cd5\u306e\u9069\u5fdc\u958b\u59cb\u5e74\u9f62\u3067\u3042\u308b\u5c31\u5b66\u524d\u5f8c\u306e\u8a55\u4fa1\u304c\u4e0d\u53ef\u6b20\u3067\u3042\u308b\u304c\uff0cADHD\u5150\u306f\u591a\u52d5\u6027\u306e\u75c7\u72b6\u3092\u6301\u3064\u305f\u3081\u9ad8\u3044\u62d8\u675f\u6027\u3092\u6301\u3064\u691c\u67fb\u306b\u306f\u9650\u754c\u304c\u3042\u308b\uff0e<br \/>\n\u4e00\u65b9\uff0cfNIRS\u306f\u4f53\u52d5\u306b\u5f37\u304f\u62d8\u675f\u6027\u304c\u4f4e\u3044\u3068\u3044\u3046\u7279\u5fb4\u3092\u6d3b\u304b\u3057\uff0c\u4ed6\u306e\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u3067\u306f\u56f0\u96e3\u3067\u3042\u3063\u305fADHD\u5150\u306e\u8a08\u6e2c\u3092\u53ef\u80fd\u3068\u3059\u308b\uff0e\u6211\u3005\u306f\uff0cADHD\u306e\u75c5\u614b\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306b\u6291\u5236\u6a5f\u80fd\u8ab2\u984c(Go\/Nogo\u8ab2\u984c)\u3092\u7528\u3044\u3066fNIRS\u8a08\u6e2c\u3092\u5b9f\u65bd\u3057\u305f\u7d50\u679c\uff0c\u5c0f\u5150ADHD\u306e\u4e2d\u5fc3\u7684\u306a\u969c\u5bb3\u3068\u306a\u308b\u6291\u5236\u6a5f\u80fd\u306b\u95a2\u9023\u3059\u308b\u53f3MFG\/IFG\u306e\u6d3b\u52d5\u4f4e\u4e0b\u3092\u96c6\u56e3\u30ec\u30d9\u30eb\u3067\u898b\u51fa\u3057\u305f\uff0e\u3055\u308c\u306b\u500b\u4eba\u30ec\u30d9\u30eb\u306b\u304a\u3044\u3066\uff0c\u305d\u308c\u3089\u306e\u8133\u9818\u57df\u306b\u8a72\u5f53\u3059\u308b\u8133\u6d3b\u52d5\u4fe1\u53f7(\u9178\u7d20\u5316Hb\u5024)\u304c\u3042\u308b\u4e00\u5b9a\u5024\u3092\u8d85\u3048\u305f\u30b1\u30fc\u30b9\u3092ADHD\u9670\u6027\u3068\u3057\u305f\u5834\u5408\u306b\uff0c\u611f\u5ea690%\u30fb\u7279\u7570\u5ea670\u3067ADHD\u3092\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3067\u304d\u308b\u65b9\u6cd5\u3092\u958b\u767a\u3057\u305f\uff0e<br \/>\n\u307e\u305f\uff0cADHD\u6cbb\u7642\u85ac\u306e\u5ba2\u89b3\u7684\u52b9\u679c\u5224\u5b9a\u6cd5\u306e\u958b\u767a\u3092\u76ee\u7684\u3068\u3057\u3066ADHD\u6cbb\u7642\u85ac(\u30e2\u30ce\u30a2\u30df\u30f3\u30a2\u30b4\u30cb\u30b9\u30c8)\u5185\u670d\u5f8c\u306e\u8133\u6a5f\u80fd\u56de\u5fa9\u3092\u691c\u8a3c\u3057\u305f\uff0e\u4e8c\u91cd\u76f2\u691c\u30d7\u30e9\u30bb\u30dc\u8a66\u9a13\u3092\u7528\u3044\u3066\u8a08\u6e2c\u3057\u305f\u7d50\u679c\uff0c\u85ac\u7269\u5185\u670d\u5f8c\u306b\u53f3MFG\/IFG\u306e\u8133\u6a5f\u80fd\u56de\u5fa9\u904e\u7a0b\u3092\u53ef\u8996\u5316\u3057\u305f\uff0e\u3053\u308c\u3089\u306e\u8ce6\u6d3b\u5316\u8133\u9818\u57df\u306f\uff0c\u30e2\u30ce\u30a2\u30df\u30f3\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306b\u95a2\u9023\u3059\u308b\u8133\u9818\u57df\u3067\u3042\u308a\uff0cfNIRS\u3092\u7528\u3044\u305f\u6211\u3005\u306e\u8a08\u6e2c\u30b7\u30b9\u30c6\u30e0\u306fADHD\u6cbb\u7642\u85ac\u306e\u85ac\u7406\u52b9\u679c\u306e\u7570\u540c\u3092\u53ef\u8996\u5316\u3057\u305f\u3068\u8003\u3048\u3089\u308c\u308b\uff0e<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u3053\u306e\u767a\u8868\u3067\u306fNIRS\u306e\u7279\u5fb4\u3092\u751f\u304b\u3057\u305fADHD\u5150\u306e\u75c5\u614b\u8a55\u4fa1\u3092\u884c\u3063\u3066\u3044\u305f\uff0e\u3053\u306e\u7814\u7a76\u3067\u306f\u611f\u5ea690%\u30fb\u7279\u7570\u5ea670\u3067ADHD\u306e\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u304c\u53ef\u80fd\u3068\u306a\u3063\u3066\u3044\u305f\uff0e\u75c5\u614b\u306e\u8a55\u4fa1\u306f\u6cbb\u7642\u65b9\u6cd5\u306e\u6c7a\u5b9a\u3084\u5909\u66f4\u306a\u3069\u69d8\u3005\u306a\u5834\u9762\u3067\u5fc5\u8981\u3067\u3042\u308a\uff0c\u6ce8\u610f\u6b20\u5982\u30fb\u591a\u52d5\u6027\u969c\u5bb3\u306e\u3088\u3046\u306a\u4ed6\u306e\u6a5f\u5668\u3067\u306f\u8a08\u6e2c\u3067\u304d\u306a\u3044\u90e8\u5206\u3092\uff0cNIRS\u3092\u4f7f\u7528\u3059\u308b\u3053\u3068\u3067\u53ef\u80fd\u306b\u306a\u308b\u3068\u3044\u3046\u3053\u3068\u3067\uff0cNIRS\u306e\u81e8\u5e8a\u5fdc\u7528\u304c\u9032\u3093\u3067\u3044\u308b\u8fd1\u5e74\u3067\u306f\u307e\u3059\u307e\u3059\u767a\u5c55\u3057\u3066\u3044\u304f\u5185\u5bb9\u3060\u3068\u611f\u3058\u308b\u3053\u3068\u304c\u3067\u304d\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"529\">\u767a\u8868\u30bf\u30a4\u30c8\u30eb\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a\u7e26\u65ad\u8a08\u6e2c\u30fb\u5927\u898f\u6a21\u8a08\u6e2c\u306b\u3088\u308bNIRS\u9451\u5225\u8a3a\u65ad\u88dc\u52a9\u6cd5\u306e\u6539\u826f<br \/>\n\u8457\u8005\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u5c0f\u6c60\u3000\u9032\u4ecb<br \/>\n\u30bb\u30c3\u30b7\u30e7\u30f3\u540d\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u30b7\u30f3\u30dd\u30b8\u30a6\u30e0<br \/>\nAbstruct\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u8fd1\u8d64\u5916\u7dda\u30b9\u30da\u30af\u30c8\u30ed\u30b9\u30b3\u30d4\u30a3(NIRS)\u306b\u3064\u3044\u3066\u306f\uff0c\u4ed6\u306e\u8133\u753b\u50cf\u8a08\u6e2c\u3068\u6bd4\u3079\u3066\u81e8\u5e8a\u73fe\u5834\u3078\u306e\u5fdc\u7528\u304c\u9032\u307f\uff0c\u5e73\u621021\u5e74\u306b\u300c\u5149\u30c8\u30dd\u30b0\u30e9\u30d5\u30a3\u30fc\u691c\u67fb\u3092\u7528\u3044\u305f\u3046\u3064\u75c7\u72b6\u306e\u9451\u5225\u8a3a\u65ad\u88dc\u52a9\u300d\u3068\u3057\u3066\u7cbe\u795e\u79d1\u9818\u57df\u3067\u306e\u521d\u306e\u5148\u9032\u533b\u7642\u3068\u3057\u3066\u8a8d\u5b9a\u3055\u308c\uff0c\u305d\u306e\u5f8c\uff0c\u5e73\u621026\u5e744\u6708\u306b\u4fdd\u967a\u53ce\u8f09\u3055\u308c\u305f\uff0eNIRS\u7814\u7a76\u306f\u65e5\u672c\u304c\u4e16\u754c\u306b\u5148\u884c\u3057\u3066\u304a\u308a\uff0c\u516c\u7684\u533b\u7642\u5236\u5ea6\u306b\u8a8d\u3081\u3089\u308c\u305f\u691c\u67fb\u3068\u3057\u3066\u3082\u65e5\u672c\u304c\u4e16\u754c\u306b\u5148\u99c6\u3057\u3066\u3044\u308b\uff0e\u305d\u306e\u4e00\u65b9\u3067\uff0c\u3053\u306e\u81e8\u5e8a\u5fdc\u7528\u306b\u3064\u3044\u3066\u306f\uff0c\u81e8\u5e8a\u7cbe\u795e\u533b\u5b66\u306e\u8996\u70b9\uff0cNIRS\u6a5f\u5668\u7279\u6027\u306e\u8996\u70b9\uff0c\u8a8d\u77e5\u5fc3\u7406\u5b66\u30fb\u8133\u79d1\u5b66\u306e\u8996\u70b9\u304b\u3089\uff0c\u6279\u8a55\u3082\u591a\u3044\uff0e\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u7cbe\u795e\u533b\u5b66\u5206\u91ce\u3067\u306f\uff0c\u3053\u308c\u3089\u306e\u8996\u70b9\u3082\u8e0f\u307e\u3048\u3066NIRS\u7814\u7a76\u3092\u9032\u3081\u3066\u3044\u308b\uff0e\u672c\u81e8\u5e8a\u5fdc\u7528\u306f\uff0c\u6162\u6027\u671f\u3092\u5bfe\u8c61\u3068\u3057\u305f\u6a2a\u65ad\u7814\u7a76\u306b\u57fa\u3065\u3044\u3066\u51fa\u3055\u308c\u305f\u7d50\u679c\u3067\u3042\u3063\u305f\uff0e\u305d\u306e\u4e00\u65b9\u6211\u3005\u306f\uff0cNIRS\u4fe1\u53f7\u306b\u3064\u3044\u3066\u306f\u75be\u60a3\u7279\u6027\u8981\u56e0\uff0c\u75c5\u614b\u9032\u884c\u8981\u56e0\uff0c\u5e74\u9f62\u3084\u6027\u5225\u306a\u3069\u975e\u7279\u7570\u7684\u8981\u56e0\u306b\u3088\u3063\u3066\u5909\u5316\u3059\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u304d\u305f\uff0e\u6211\u3005\u306f\u73fe\u5728\uff0c\u7d71\u5408\u5931\u8abf\u75c7\u767a\u75c7\u524d\u5f8c\u306e\u8133\u753b\u50cf\u7e26\u65ad\u8a08\u6e2c\u30d7\u30ed\u30b8\u30a7\u30af\u30c8(IN-STEP\u7814\u7a76)\u3092\u5b9f\u65bd\u3057\u3066\u304a\u308a\uff0c\u7e26\u65ad\u30c7\u30fc\u30bf\u3092\u4e2d\u5fc3\u306b\u7814\u7a76\u3092\u91cd\u306d\u3066\u3044\u308b\uff0e\u7e26\u65ad\u7814\u7a76\u30c7\u30fc\u30bf\u3092\u7528\u3044\u305f\u7d50\u679c\u3068\u3057\u3066\uff0c\u2460\u521d\u767a\u7d71\u5408\u5931\u8abf\u75c7\u306e\u4e0a\u524d\u982d\u56de\u6d3b\u52d5\u304c\u81e8\u5e8a\u4e88\u5f8c\u3092\u4e88\u6e2c\u3067\u304d\u308b\uff0c\u2461\u7d71\u5408\u5931\u8abf\u75c7\u306e\u767a\u75c7\u30ea\u30b9\u30af\u7fa4\uff0c\u521d\u767a\u7fa4\u306f\uff0c\u5e74\u9f62\uff0c\u6027\u5225\u3092\u88dc\u6b63\u3059\u308c\u3070\u4fdd\u967a\u53ce\u8f09\u3055\u308c\u305fNIRS\u6280\u8853\u3092\u7528\u3044\u306680%\u3092\u8d85\u3048\u3066\u7cbe\u795e\u75c5\u570f\u3068\u5224\u65ad\u3067\u304d\u308b(Koike\u3089\uff0c\u67fb\u8aad\u4e2d)\u3053\u3068\u3092\u5f97\u305f\uff0e\u672c\u767a\u8868\u3067\u306f\uff0c\u3053\u308c\u3089\u306e\u7814\u7a76\u6210\u679c\u3092\u7d39\u4ecb\u3057\uff0c\u6642\u9593\u304c\u8a31\u305b\u3070\u73fe\u5728\u5b9f\u65bd\u4e2d\u306e\u75ab\u5b66\u7d71\u8a08\u624b\u6cd5\u306b\u57fa\u3065\u304f\u5927\u898f\u6a21\u89e3\u6790\uff0cmulti-distance and whole-head probe\u3092\u7528\u3044\u305f\u5b89\u9759\u6642NIRS\u8133\u6d3b\u52d5\u89e3\u6790\u7d50\u679c\u3082\u7d39\u4ecb\u3057\u305f\u3044\uff0e<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u3053\u306e\u767a\u8868\u3067\u306f\uff0c2015\u5e74\u306b\u4fdd\u967a\u9069\u7528\u304c\u306a\u3055\u308c\u305fNIRS\u3092\u7528\u3044\u305f\u7cbe\u795e\u75be\u60a3\u306e\u8a3a\u65ad\u306b\u3064\u3044\u3066\u8ff0\u3079\u3089\u308c\u3066\u3044\u305f\uff0eNIRS\u306e\u81e8\u5e8a\u5fdc\u7528\u306b\u306f\u69d8\u3005\u306a\u610f\u898b\u304c\u3042\u308b\u304c\uff0c\u8133\u6d3b\u52d5\u306b\u3088\u308a\u4e88\u5f8c\u306e\u4e88\u6e2c\u304c\u53ef\u80fd\u3067\u3042\u3063\u305f\u308a\uff0c80%\u3092\u8d85\u3048\u3066\u7cbe\u795e\u75c5\u570f\u3067\u3042\u308b\u3053\u3068\u304c\u7d50\u679c\u3068\u3057\u3066\u5f97\u3089\u308c\u305f\u305f\u3081\uff0c\u81e8\u5e8a\u5fdc\u7528\u304c\u53ef\u80fd\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u5185\u5bb9\u3060\u3063\u305f\uff0e\u6765\u5e74\u5ea6\u306e\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a\u3067\u306f\uff0cNIRS\u306e\u81e8\u5e8a\u5fdc\u7528\u306b\u3064\u3044\u3066\u3092\u8b70\u984c\u3068\u3057\u3066\u7528\u3044\u308b\u306e\u3067\uff0c\u305c\u3072\u53c2\u52a0\u3057\u3066\u307f\u305f\u3044\u3068\u601d\u3046\uff0e<br \/>\n&nbsp;<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"529\">\u767a\u8868\u30bf\u30a4\u30c8\u30eb\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a NIRS\u3092\u7528\u3044\u305f\u6c17\u5206\u8a08\u6e2c<br \/>\n\u8457\u8005\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u4f50\u85e4\u3000\u5927\u6a39<br \/>\n\u30bb\u30c3\u30b7\u30e7\u30f3\u540d\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u30b7\u30f3\u30dd\u30b8\u30a6\u30e0<br \/>\nAbstruct\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a 1\u306f\u3058\u3081\u306b<br \/>\n\u8fd1\u8d64\u5916\u5206\u5149\u6cd5(Near-Infrared Spectroscopy: NIRS)\u3092\u5229\u7528\u3057\u305f\u8133\u6a5f\u80fd\u8a08\u6e2c\u6280\u8853\u306f\uff0c\u8a08\u6e2c\u74b0\u5883\u306e\u9650\u5b9a\u304c\u5c11\u306a\u304f\uff0c\u7c21\u4fbf\u6027\u30fb\u5b9f\u7528\u6027\u306b\u512a\u308c\u305f\u7279\u5fb4\u3092\u6301\u3064\uff0e\u88c5\u7f6e\u306e\u5c0f\u578b\u5316\u3082\u9032\u307f\uff0c\u5b66\u8853\u7814\u7a76\u3092\u7aef\u7dd2\u3068\u3057\u3066\u69d8\u3005\u306a\u5fdc\u7528\u306e\u5b9f\u73fe\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u308b\uff0e\u6211\u3005\u306f\uff0c\u30d2\u30c8\u306b\u304a\u3044\u3066\u7279\u306b\u767a\u9054\u3057\u3066\u3044\u308b\u524d\u982d\u8449\u306b\u7740\u76ee\u3057\u3066\uff0cNIRS\u7814\u7a76\u3092\u9032\u3081\uff0c\u30ef\u30fc\u30ad\u30f3\u30b0\u30e1\u30e2\u30ea(WM)\u8ab2\u984c\u306b\u4f34\u3046\u8133\u6d3b\u52d5\u4fe1\u53f7\u304c\uff0c\u4e3b\u89b3\u7684\u306b\u8a55\u4fa1\u3057\u305f\u6291\u3046\u3064\u533a\u5206\u30b9\u30b3\u30a2\u3068\u95a2\u9023\u3059\u308b\u3053\u3068\u3092\u898b\u51fa\u3057\u305f\uff0e\u672c\u767a\u8868\u3067\u306f\uff0c\u3053\u306e\u73fe\u8c61\u3092\u6c17\u5206\u8a08\u6e2c\u3068\u3057\u3066\u5229\u7528\u3057\uff0c\u5fa9\u8077\u652f\u63f4\u30d7\u30ed\u30b0\u30e9\u30e0\u306e\u53c2\u52a0\u8005\u306b\u9069\u7528\u3057\u305f\u7814\u7a76\u3092\u7d39\u4ecb\u3059\u308b\uff0e\u307e\u305f\uff0c\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u5f71\u97ff\u3092\u691c\u8a0e\u3059\u308b\u624b\u6cd5\u3067\u3042\u308b\u6025\u6027\u30c8\u30ea\u30d7\u30c8\u30d5\u30a1\u30f3\u67af\u6e07\u75c7(Acute Tryptophan Depletion: ATD)\u3092\u7528\u3044\u305f\u7814\u7a76\u306b\u3088\u308a\u6c17\u5206\u8a08\u6e2c\u306e\u80cc\u666f\u306b\u3042\u308b\u751f\u7406\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u3064\u3044\u3066\u8003\u5bdf\u3059\u308b\uff0e<br \/>\n2\uff0e\u5fa9\u8077\u652f\u63f4\u30d7\u30ed\u30b0\u30e9\u30e0\u306b\u304a\u3051\u308b\u6c17\u5206\u8a08\u6e2c<br \/>\nNIRS\u3092\u7528\u3044\u305f\u6c17\u5206\u8a08\u6e2c\u306e\u6709\u52b9\u6027\u3092\u691c\u8a0e\u3059\u308b\u305f\u3081\uff0c\u5fa9\u8077\u652f\u63f4\u30d7\u30ed\u30b0\u30e9\u30e0\u53c2\u52a0\u8005\u306b\u5bfe\u3057\u3066NIRS\u8a08\u6e2c\u304a\u3088\u3073\u6c17\u5206\u306e\u4e3b\u89b3\u8a55\u4fa1(\u8cea\u554f\u7d19)\u3092\u7d99\u7d9a\u7684\u306b\u5b9f\u65bd\u3057\u305f\uff0e\u307e\u305f\uff0c\u88ab\u9a13\u8005\u304c\u81ea\u5206\u306e\u72b6\u614b\u3092\u5b89\u5b9a\u3057\u3066\u628a\u63e1\u3067\u304d\u3066\u3044\u308b\u304b\uff0c\u81e8\u5e8a\u5fc3\u7406\u58eb\u306e\u5224\u65ad\u7d50\u679c\u3082\u53d6\u5f97\u3057\u305f\uff0e\u305d\u306e\u7d50\u679c\uff0c\u81ea\u5206\u306e\u72b6\u614b\u3092\u5b89\u5b9a\u3057\u3066\u628a\u63e1\u3067\u304d\u3066\u3044\u308b\u6642\u671f\u306b\u306f\uff0c\u6c17\u5206\u3068\u95a2\u9023\u3059\u308b\u8133\u6d3b\u52d5\u4fe1\u53f7(\u6c17\u5206\u8133\u6307\u6a19)\u3068\u4e3b\u89b3\u7684\u306a\u6291\u3046\u3064\u6c17\u5206\u30b9\u30b3\u30a2\u306e\u9593\u306b\u9ad8\u3044\u76f8\u95a2\u304c\u898b\u3089\u308c\u305f\uff0e\u4e00\u65b9\uff0c\u81ea\u5206\u306e\u72b6\u614b\u8a55\u4fa1\u304c\u4e0d\u5b89\u5b9a\u306a\u6642\u671f\u306b\u306f\u4e00\u8cab\u3057\u305f\u50be\u5411\u304c\u898b\u3089\u308c\u306a\u304b\u3063\u305f\uff0e\u3053\u306e\u7d50\u679c\u306f\uff0cNIRS\u3092\u7528\u3044\u305f\u6c17\u5206\u8a08\u6e2c\u304c\uff0c\u5fa9\u8077\u652f\u63f4\u30d7\u30ed\u30b0\u30e9\u30e0\u53c2\u52a0\u8005\u306e\u72b6\u614b\u3092\u5ba2\u89b3\u7684\u306b\u628a\u63e1\u3059\u308b\u624b\u6bb5\u3068\u3057\u3066\u6709\u7528\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u5506\u3059\u308b\uff0e<br \/>\n3\uff0e\u6c17\u5206\u304a\u3088\u3073NIRS\u4fe1\u53f7\u306b\u5bfe\u3059\u308b\u30bb\u30ed\u30c8\u30cb\u30f3\u6a5f\u80fd\u306e\u5f71\u97ff<br \/>\n\u30bb\u30ed\u30c8\u30cb\u30f3\u306f\uff0c\u6c17\u5206\u6291\u5236\u3068\u8a8d\u77e5\u6a5f\u80fd\u306e\u4e21\u65b9\u3078\u306e\u95a2\u4e0e\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u308b\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u3067\u3042\u308b\uff0e\u672c\u7814\u7a76\u3067\u306f\uff0c\u6c17\u5206\u304a\u3088\u3073\u8133\u6d3b\u52d5\u4fe1\u53f7\u306b\u5bfe\u3059\u308b\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u5f71\u97ff\u3092\u691c\u8a0e\u3059\u308b\u305f\u3081\uff0c\u30bb\u30ed\u30c8\u30cb\u30f3\u304c\u4f4e\u6e1b\u3057\u305f\u72b6\u614b\u3092\u4f5c\u308a\u51fa\u3059\u6025\u6027\u30c8\u30ea\u30d7\u30c8\u30d5\u30a1\u30f3\u67af\u6e07\u75c7(ATD)\u3092\u4f75\u7528\u3057\u305f\u5149\u30c8\u30dd\u30b0\u30e9\u30d5\u30a3\u8a08\u6e2c\u3092\u5b9f\u65bd\u3057\u305f\uff0e\u5065\u5e38\u88ab\u9a13\u800529\u540d\u306b\u5bfe\u3057\u3066\u30c0\u30d6\u30eb\u30d6\u30e9\u30a4\u30f3\u30c9\u30c6\u30b9\u30c8\u3092\u5b9f\u65bd\u3057\uff0cATD\u6761\u4ef6\u3068\u7d71\u5236\u6761\u4ef6\u3092\u6bd4\u8f03\u3057\u305f\u7d50\u679c\uff0cATD\u6761\u4ef6\u3067\u306f\uff0c\u30dd\u30b8\u30c6\u30a3\u30d6\u6c17\u5206\u30b9\u30b3\u30a2\u304c\u4f4e\u4e0b\u3059\u308b\u3068\u5171\u306b\u8a00\u8a9e\u6027WM\u8ab2\u984c\u306b\u4f34\u3046\u8133\u6d3b\u52d5\u4fe1\u53f7\u304c\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u305f\uff0e\u3053\u306e\u7d50\u679c\u306f\uff0c\u5f93\u6765\u306e\u6c17\u5206\u8a08\u6e2c\u3067\u898b\u3089\u308c\u305f\u76f8\u95a2\u95a2\u4fc2\u3068\u4e00\u81f4\u3057\uff0c\u4e3b\u89b3\u7684\u306a\u6c17\u5206\u30b9\u30b3\u30a2\u3068\u8133\u6d3b\u52d5\u4fe1\u53f7\u306e\u4e21\u65b9\u306b\u30bb\u30ed\u30c8\u30cb\u30f3\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u5506\u3059\u308b\uff0e\u305f\u3060\u3057\uff0c\u305d\u308c\u3089\u306e\u5909\u5316\u91cf\u306e\u500b\u4eba\u5dee\u306b\u6709\u610f\u306a\u76f8\u95a2\u95a2\u4fc2\u306f\u306a\u304f\uff0c\u7d50\u679c\u306e\u89e3\u91c8\u306b\u3064\u3044\u3066\u306f\u66f4\u306a\u308b\u691c\u8a0e\u304c\u5fc5\u8981\u3067\u3042\u308b\uff0e<br \/>\n4\uff0e\u304a\u308f\u308a\u306b<br \/>\nNIRS\u306f\uff0c\u65e5\u5e38\u74b0\u5883\u4e0b\u306e\u8133\u6a5f\u80fd\u3092\u7c21\u4fbf\u306b\u8a08\u6e2c\u3067\u304d\u308b\u6280\u8853\u3067\u3042\u308a\uff0c\u305d\u306e\u7279\u5fb4\u3092\u751f\u304b\u3057\u305f\u7814\u7a76\u304a\u3088\u3073\u5fdc\u7528\u304c\u6307\u5411\u3055\u308c\u3066\u3044\u308b\uff0e\u7279\u306b\uff0c\u5927\u304d\u306a\u793e\u4f1a\u554f\u984c\u306b\u306a\u3063\u3066\u3044\u308b\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u306b\u95a2\u3057\u3066\u306f\uff0c\u5ba2\u89b3\u7684\u306a\u8a55\u4fa1\u65b9\u6cd5\u3068\u3057\u3066\u5f79\u7acb\u3064\u53ef\u80fd\u6027\u304c\u3042\u308b\uff0e\u4eca\u5f8c\uff0cNIRS\u4fe1\u53f7\u306e\u610f\u5473\u7406\u89e3\u3092\u6df1\u3081\uff0c\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u5411\u4e0a\u306b\u8ca2\u732e\u3059\u308b\u6280\u8853\u3068\u3057\u3066\u793e\u4f1a\u5b9f\u88c5\u3057\u3066\u3044\u304d\u305f\u3044\uff0e<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u3053\u306e\u767a\u8868\u3067\u306f\uff0cNIRS\u306b\u3088\u308b\u6c17\u5206\u8a08\u6e2c\u304c\u88ab\u9a13\u8005\u306e\u72b6\u614b\u3092\u5ba2\u89b3\u7684\u306b\u628a\u63e1\u3059\u308b\u65b9\u6cd5\u3068\u3057\u3066\u6709\u7528\u3067\u3042\u308b\u3053\u3068\u304c\u8ff0\u3079\u3089\u308c\u3066\u3044\u305f\uff0e\u3053\u306e\u7814\u7a76\u3067\u884c\u308f\u308c\u3066\u3044\u308b\u6c17\u5206\u8a08\u6e2c\u306f\u81e8\u5e8a\u3067\u7528\u3044\u3089\u308c\u3066\u3044\u308b\u7cbe\u795e\u75be\u60a3\u306e\u9451\u5225\u3068\u901a\u305a\u308b\u3082\u306e\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u305f\uff0e\u3057\u305f\u304c\u3063\u3066\uff0c\u3053\u306e\u7814\u7a76\u7d50\u679c\u3092\u8e0f\u307e\u3048\u305f\u3046\u3048\u3067\u7cbe\u795e\u75be\u60a3\u3068\u8133\u6d3b\u52d5\u306b\u3064\u3044\u3066\u7814\u7a76\u3092\u884c\u3046\u3053\u3068\u306b\u3088\u308a\u6b63\u78ba\u306a\u5224\u65ad\u3084\u3088\u308a\u5e83\u7bc4\u56f2\u306e\u75be\u60a3\u306b\u5bfe\u5fdc\u3057\u305f\u9451\u5225\u304c\u53ef\u80fd\u306b\u306a\u308b\u3068\u8003\u3048\uff0c\u3053\u308c\u304b\u3089\u3055\u3089\u306b\u6df1\u3081\u3066\u3044\u304f\u3068\u9762\u767d\u3044\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u601d\u3048\u308b\u5185\u5bb9\u3060\u3063\u305f\uff0e<br \/>\n&nbsp;<br \/>\n<strong>\u5b66\u4f1a\u53c2\u52a0\u5831\u544a\u66f8<\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"147\"><strong>\u00a0<\/strong><br \/>\n<strong>\u5831\u544a\u8005\u6c0f\u540d<\/strong><\/td>\n<td width=\"373\">&nbsp;<br \/>\n\u5409\u6b66\u3000\u6c99\u898f<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u767a\u8868\u8ad6\u6587\u30bf\u30a4\u30c8\u30eb<\/strong><\/td>\n<td width=\"373\">\u6700\u9069\u5316HRF\u3068BF\u306b\u3088\u308bfNIRS\u306b\u304a\u3051\u308b\u6d3b\u6027\u89e3\u6790\u306b\u5bfe\u3059\u308b\u30a2\u30d7\u30ed\u30fc\u30c1<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u767a\u8868\u8ad6\u6587\u82f1\u30bf\u30a4\u30c8\u30eb<\/strong><\/td>\n<td width=\"373\">Adaptive HRF and BF approaches to fNIRS activation analysis<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u8457\u8005<\/strong><\/td>\n<td width=\"373\">\u5409\u6b66\u3000\u6c99\u898f<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u4e3b\u50ac<\/strong><\/td>\n<td width=\"373\">\u533b\u7642\u60c5\u5831\u30b7\u30b9\u30c6\u30e0\u7814\u7a76\u5ba4<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u8b1b\u6f14\u4f1a\u540d<\/strong><\/td>\n<td width=\"373\">Neuroinformatics2016<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u4f1a\u5834<\/strong><\/td>\n<td width=\"373\">University of Reading<\/td>\n<\/tr>\n<tr>\n<td width=\"147\"><strong>\u958b\u50ac\u65e5\u7a0b<\/strong><\/td>\n<td width=\"373\">2016\/09\/03-2016\/09\/04<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<br \/>\n&nbsp;<\/p>\n<ol>\n<li>\u8b1b\u6f14\u4f1a\u306e\u8a73\u7d30<\/li>\n<\/ol>\n<p>2016\/09\/03\u304b\u30892016\/09\/04\u306b\u304b\u3051\u3066\uff0cReading University\u306b\u3066\u958b\u50ac\u3055\u308c\u307e\u3057\u305fNeuroinformatics2016\u306b\u53c2\u52a0\u3044\u305f\u3057\u307e\u3057\u305f\uff0e\u4ed6\u306b\u3053\u306e\u5b66\u4f1a\u306f\uff0cincf\u306b\u3088\u3063\u3066\u4e3b\u50ac\u3055\u308c\u305f\u5b66\u4f1a\u3067\uff0c\u3053\u306e\u5b66\u4f1a\u306f\uff0c\u7d50\u679c\u306e\u5171\u6709\u3068\u89e3\u6790\u65b9\u6cd5\u306e\u63d0\u4f9b\u3092\u76ee\u7684\u3068\u3057\u3066\u958b\u50ac\u3055\u308c\u307e\u3057\u305f\uff0e\u307e\u305f\u3053\u306e\u5b66\u4f1a\u5185\u3067\u306f\uff0c\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u30b7\u30b9\u30c6\u30e0\u3084\u753b\u50cf\u5316\uff0c\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u30e2\u30c7\u30ea\u30f3\u30b0\u304c\u30bb\u30c3\u30b7\u30e7\u30f3\u5185\u3067\u767a\u8868\u3055\u308c\u307e\u3057\u305f\uff0e<br \/>\n\u672c\u7814\u7a76\u5ba4\u304b\u3089\u4ed6\u306b\uff0c\u5ee3\u5b89\u5148\u751f\uff0c\u65e5\u548c\u5148\u751f\uff0cM1\u306e\u8429\u539f\u3055\u3093\uff0c\u7389\u57ce\u3055\u3093\u304c\u53c2\u52a0\u3057\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<ol start=\"2\">\n<li>\u7814\u7a76\u767a\u8868\n<ul>\n<li>\u767a\u8868\u6982\u8981<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n<p>\u79c1\u306f3\u65e5\u306e17:30\u304b\u3089\u306ePOSTER AND DEMO RECEPTION\u306b\u53c2\u52a0\u3044\u305f\u3057\u307e\u3057\u305f\uff0e\u30dd\u30b9\u30bf\u30fc\u524d\u3067\u306e\u8b70\u8ad6\u304c\u884c\u308f\u308c\u307e\u3057\u305f\uff0e<br \/>\n\u4eca\u56de\u306e\u767a\u8868\u306f\uff0cfNIRS\u306b\u3088\u308b\u8a08\u6e2c\u30c7\u30fc\u30bf\u306e\u89e3\u6790\u65b9\u6cd5\u306b\u3064\u3044\u3066\u306e\u767a\u8868\u3092\u884c\u3044\u307e\u3057\u305f\uff0e\u4ee5\u4e0b\u306b\u6284\u9332\u3092\u8a18\u8f09\u81f4\u3057\u307e\u3059\uff0e<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"529\">Functional Near Infrared Spectroscopy is one of the measurement methods for elucidation cerebral function. Measuring cerebral bloodflow change by using fNIRS, brain activation can be judged. GLM is one of the judging methods of brain activation using cerebral bloodflow change. In GLM, brain activation is judged by regression analysis of hemodynamic model and measurement data[1][2]. This hemodynamic model is created by convolution of hemodynamic response function(HRF)[3] and rectangular function based on the experimental design. Rectangular function and HRF used in thin method is the same, regardless subjects, measurement region and experimental design. But there is a possibility HRF varies depend on brain region and tasks and within subjects[3][4]. Therefore, each HRF is not always the same as general HRF. The method using hemodynamic model made with same HRF and rectangular function can\u2019t analyze along measurement data. So, it is considered that this method is unconvincing in judging brain activation. Therefore, accurate judging method is needed. Rectangular function containing variation information of cerebral activation can be determined by optimizing the function based on measurement data. Also, measurement data can be expressed exactly by optimizing HRF containing timing information based on rectangular function and measurement data. In this way, brain activation is judged exactly. Hemodynamic model matched with fNIRS data was made by optimizing HRF after optimizing rectangular function. HRF parameters are the first peak delay, the undershoot delay and amplitude ratio between the first peak and the undershoot. In optimizing rectangular function, the size of function was determined as the amount of change after 5 seconds which is maximum arrival time. Regression analysis performs on measurement data and hemodynamic model made with rectangular function and HRF. Index of optimization is t value of regression coefficient. HRF parameters are determined when t value reaches maximum. Using 3 parameters of HRF, cerebral function of each subjects and cerebral region was examined.<br \/>\n&nbsp;<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<ul>\n<li>\u8cea\u7591\u5fdc\u7b54<\/li>\n<\/ul>\n<p>\u4eca\u56de\u306e\u8b1b\u6f14\u767a\u8868\u3067\u306f\uff0c\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u8cea\u7591\u3092\u53d7\u3051\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<br \/>\n<strong>\u30fb\u8cea\u554f\u5185\u5bb9<\/strong><strong>1<\/strong><br \/>\n\u4f7f\u7528\u6a5f\u5668\u3067\u3042\u308bNIRS\u306b\u3064\u3044\u3066\u306e\u8cea\u554f\u3092\u3044\u305f\u3060\u304d\u307e\u3057\u305f\uff0e\u3057\u305f\u304c\u3063\u3066NIRS\u306b\u3088\u3063\u3066\u8a08\u6e2c\u3057\u3066\u3044\u308b\u30c7\u30fc\u30bf\u304c\u5b9f\u969b\u306b\u4f55\u3092\u8a08\u6e2c\u3057\u3069\u306e\u3088\u3046\u306a\u5185\u5bb9\u3092\u8868\u3057\u3066\u3044\u308b\u306e\u304b\u3092\u8aac\u660e\u3057\u307e\u3057\u305f\uff0c\u307e\u305f\uff0c\u8a08\u6e2c\u539f\u7406\u306b\u3064\u3044\u3066\u8fd1\u8d64\u5916\u5149\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u3053\u3068\u306a\u3069\u3092\u8aac\u660e\u3057\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<br \/>\n<strong>\u30fb\u8cea\u554f\u5185\u5bb9<\/strong><strong>2<\/strong><br \/>\n\u30e1\u30a4\u30f3\u306e\u7d50\u679c\u304c\u4f55\u3092\u793a\u3057\u3066\u3044\u308b\u306e\u304b\u3092\u8aac\u660e\u3057\u3066\u307b\u3057\u3044\u3068\u3044\u3046\u8cea\u554f\u304c\u3042\u308a\u307e\u3057\u305f\uff0e\u3057\u305f\u304c\u3063\u3066\u79c1\u306f\uff0c\u3053\u306e\u7814\u7a76\u306e\u30b3\u30f3\u30bb\u30d7\u30c8\u304b\u3089\u8aac\u660e\u3092\u884c\u3044\u307e\u3057\u305f\uff0e\u30b3\u30f3\u30bb\u30d7\u30c8\u3068\u6bd4\u8f03\u3057\u306a\u304c\u3089\u5b9f\u969b\u306b\u51fa\u305f\u7d50\u679c\u304c\u5b9f\u884c\u8ab2\u984c\u306e\u523a\u6fc0\u306e\u5927\u304d\u3055\u3092\u793a\u3059\u3053\u3068\u304c\u3067\u304d\uff0c\u6642\u7cfb\u5217\u306e\u5909\u5316\u306b\u3088\u3063\u3066\u3069\u306e\u3088\u3046\u306b\u5909\u308f\u3063\u3066\u3044\u308b\u306e\u304b\uff0c\u307e\u305fHRF\u306e\u6700\u9069\u5316\u306b\u3088\u3063\u3066\u523a\u6fc0\u306b\u5bfe\u3059\u308b\u8840\u6d41\u53cd\u5fdc\u306e\u901f\u3055\u306e\u691c\u8a0e\u304c\u53ef\u80fd\u306b\u306a\u308b\u3053\u3068\u3092\u8aac\u660e\u3057\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<br \/>\n<strong>\u30fb\u8cea\u554f\u5185\u5bb9<\/strong><strong>3<\/strong><br \/>\nCross-validation\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u306e\u304b\u3092\u8cea\u554f\u3055\u308c\u307e\u3057\u305f\uff0e\u3057\u305f\u304c\u3063\u3066\u79c1\u306f\u3053\u306e\u7814\u7a76\u3067\u306f\u56de\u5e30\u5206\u6790\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u306e\u3067\uff0c\u4f7f\u7528\u3057\u3066\u3044\u306a\u3044\u3068\u8fd4\u7b54\u3057\u307e\u3057\u305f\uff0e<br \/>\n<strong>\u00a0<\/strong><br \/>\n<strong>\u30fb\u8cea\u554f\u5185\u5bb9<\/strong><strong>4<\/strong><br \/>\n\u8ab2\u984c\u3067\u3042\u308bn-back\u30bf\u30b9\u30af\u3092\u77e5\u3089\u306a\u3044\u65b9\u304c\u591a\u304b\u3063\u305f\u306e\u3067\uff0c\u8ab2\u984c\u306e\u8aac\u660e\u3068\u96e3\u6613\u5ea6\u306b\u3088\u308a\u3069\u3046\u9055\u3046\u306e\u304b\u3092\u8aac\u660e\u3057\u307e\u3057\u305f\uff0e<br \/>\n<strong>\u30fb\u8cea\u554f\u5185\u5bb9<\/strong><strong>5<\/strong><br \/>\n\u4eca\u56de\u89e3\u6790\u3057\u3066\u3044\u308b\u30c7\u30fc\u30bf\u306fOxy-Hb\u306e\u307f\u3067\uff0cDeoxy-Hb\u306f\u4f7f\u7528\u3057\u3066\u3044\u306a\u3044\u306e\u304b\u3068\u805e\u304b\u308c\u305f\u306e\u3067<br \/>\nOxy-Hb\u306e\u307f\u4f7f\u7528\u3057\u3066\u3044\u308b\u3068\u8fd4\u7b54\u3057\u307e\u3057\u305f\uff0e\u7406\u7531\u3068\u3057\u3066Deoxy-Hb\u3067\u306eHRF\u306b\u3064\u3044\u3066\u3042\u307e\u308a\u308f\u304b\u3063\u3066\u3044\u306a\u3044\u3053\u3068\u3092\u8aac\u660e\u3057\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<ul>\n<li>\u611f\u60f3<\/li>\n<\/ul>\n<p>\u767a\u8868\u524d\u306f\u81ea\u5206\u306e\u82f1\u8a9e\u304c\u3069\u3053\u307e\u3067\u901a\u3058\u308b\u306e\u304b\uff0c\u304d\u3061\u3093\u3068\u8fd4\u7b54\u3067\u304d\u308b\u306e\u304b\u3068\u4e0d\u5b89\u304c\u5927\u304d\u304b\u3063\u305f\u3067\u3059\u304c\uff0c\u5b9f\u969b\u306b\u767a\u8868\u3057\u305f\u969b\u306b\u306f\uff0c\u805e\u304d\u8fd4\u3059\u3068\u5206\u304b\u308a\u3084\u3059\u304f\u3086\u3063\u304f\u308a\u3068\u8cea\u554f\u3057\u306a\u304a\u3057\u3066\u304f\u3060\u3055\u3063\u305f\u308a\u3057\u3066\uff0c\u3000\u53d7\u3051\u7b54\u3048\u304c\u3067\u304d\u3066\u3044\u305f\u3068\u601d\u3044\u307e\u3059\uff0e\u307e\u305f\uff0c\u81ea\u5206\u304c\u60f3\u50cf\u3057\u3066\u3044\u305f\u3088\u308a\u3082NIRS\u3084HRF\u306b\u3064\u3044\u3066\u3054\u5b58\u3058\u306a\u3044\u65b9\u304c\u591a\u304b\u3063\u305f\u306e\u3067\uff0c\u8aac\u660e\u8cc7\u6599\u3092\u4f5c\u6210\u3057\u3066\u3044\u304f\u3079\u304d\u3060\u3063\u305f\u3068\u601d\u3044\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<ol start=\"3\">\n<li>\u8074\u8b1b<\/li>\n<\/ol>\n<p>\u4eca\u56de\u306e\u8b1b\u6f14\u4f1a\u3067\u306f\uff0c\u4e0b\u8a18\u306e2\u4ef6\u306e\u767a\u8868\u3092\u8074\u8b1b\u3057\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"529\">\u767a\u8868\u30bf\u30a4\u30c8\u30eb\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a\u3000Whole brain fMRI activity at a high temporal resolution: A novel analytic framework<br \/>\n\u8457\u8005\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a \u00a0Niels Janssen<br \/>\n\u30bb\u30c3\u30b7\u30e7\u30f3\u540d\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a Neuroimaging I<br \/>\nAbstruct\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a We have developed a new framework for the analysis of functional Magnetic Resonance Imaging (fMRI) data. Whereas current analytic techniques primarily yield static, time-invariant maps of fMRI activity (Smith et al., 2004), our new technique yields dynamic, time-variant videos of whole-brain fMRI activity. The new framework relies on a fundamentally different method of fMRI BOLD signal extraction. Specifically, instead of the standard volume-based signal extraction, the new method extracts the fMRI BOLD signal based on the veridical MRI slice acquisition times. This yields an fMRI signal that is more temporally accurate (Sladky et al., 2011). In addition, we improved the temporal resolution by presenting each slice to a different point in the progression of the BOLD signal [see also Price et al. (1999)]. The fMRI BOLD signal is then extracted using non-standard statistical modeling techniques. Specifically, the fMRI data are first broken up into epochs that are time-locked to the onset of a stimulus. Next, in line with techniques used in EEG (Janssen et al., 2014), statistical models are run at each time-point in the epoch. As the baseline, we used the fMRI signal intensity values available at time-point 0. For this particular choice of baseline, modeling involves extracting the fMRI BOLD signal across time points in the epoch. The number of available timepoints in the epoch (and therefore the temporal resolution) is scalable, up to a maximum that is determined by the rate at which MRI slices are acquired (typically on the order of tens of milliseconds). In order to account for the full complexity of the statistical model, we used Linear Mixed Effect modeling (Pinheiro and Bates, 2000). Our method yields an fMRI signal for every voxel in the brain that is more temporally accurate and of a much higher temporal resolution that is available in current frameworks.<br \/>\nThe data manipulation in the new framework relies on functions written as part of the neuro-imaging data analysis package FSL (Smith et al., 2004) and various Python scripts of which the NiBabel package for reading neuro-imaging data forms an indispensable part (http:\/\/nipy.org\/nibabel\/). Statistical modeling of first order individual participant data relied on the data.table and lme4 packages available in the software R (Douglas et al., 2015). Higher order modeling was performed with the randomise function of FSL (Winkler et al., 2014). A key characteristic of the current approach is that it does not rely on data averaging but uses all data points from all epochs in an experiment to model the signal. Advantages of using this pipeline are that statistical modeling of first-order fMRI data is greatly simplified and handled by R. Disadvantages are the slow speed of R, and the large file sizes due to the long data table format requirements imposed by R.<br \/>\nWe will illustrate the new technique in the context of fMRI data collected during a visual object naming experiment. We will use these data to explore the spatio-temporal dynamics of the whole-brain fMRI BOLD signal at 390\u00a0ms temporal resolution, focusing on task-based functional connectivity. Our new framework can be easily applied to data collected with other types of tasks and provides a novel opportunity to gain insight into the spatio-temporal dynamics of fMRI activity during cognitive tasks.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u3053\u306e\u767a\u8868\u3067\u306fMRI\u30c7\u30fc\u30bf\u306e\u89e3\u6790\u624b\u6cd5\u3092\u63d0\u6848\u3057\u3066\u3044\u307e\u3057\u305f\uff0e\u523a\u6fc0\u3092\u4e0e\u3048\u305f\u6642\u306e\u30b9\u30e9\u30a4\u30b9\u3092\u7528\u3044\u3066\u30dc\u30ea\u30e5\u30fc\u30e0\u306e\u518d\u69cb\u6210\u3092\u3057\u3066\u3044\u307e\u3057\u305f\uff0e\u3053\u306e\u65b9\u6cd5\u3092\u4f7f\u7528\u3059\u308b\u3068\u523a\u6fc0\u4ed8\u8fd1\u306e\u8133\u72b6\u614b\u3092\u89b3\u5bdf\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u3063\u3066\u3044\u307e\u3057\u305f\uff0e\u3057\u304b\u3057\uff0c\u3053\u306e\u65b9\u6cd5\u3067\u306f\u523a\u6fc0\u306b\u3088\u308b\u8133\u6d3b\u52d5\u306e\u5909\u5316\u306e\u307f\u3092\u898b\u3089\u308c\u308b\u3068\u306f\u9650\u3089\u306a\u3044\u306e\u3067\uff0c\u691c\u8a0e\u3092\u884c\u3046\u5fc5\u8981\u304c\u3042\u308b\u3068\u611f\u3058\u307e\u3057\u305f\uff0e<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"529\">\u767a\u8868\u30bf\u30a4\u30c8\u30eb\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1aMechanisms underlying different onset patterns of focal seizures<br \/>\n\u8457\u8005\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a Yujiang Wang<br \/>\n\u30bb\u30c3\u30b7\u30e7\u30f3\u540d\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a Brain Disorders I<br \/>\nAbstruct\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff1a Focal seizures typically begin with an electrographic onset pattern that is highly stereotyped in individual patients. Qualitative classifications of these onset patterns describe two frequently occurring waveforms \u2013 low amplitude fast oscillations (LAF), or high amplitude spikes (HAS). Interestingly, only the former of the patterns is associated with a good surgical outcome. Given the importance of this clinical distinction, we therefore explored whether these two patterns arise from fundamentally different\u00a0 spatio-temporal dynamics.<br \/>\nWe used a previously established computational model of neocortical tissue, and validated it as an adequate model using clinical recordings of focal seizures. Using this model we then investigated the possible mechanisms underlying the different focal seizure onset patterns.<br \/>\nWe show that the two patterns are associated with different mechanisms at the spatial scale of a single ECoG electrode. The LAF onset is initiated by independent patches of localised activity, which slowly invade the surrounding tissue and coalesce over time (see Figure 1A). In contrast, the HAS onset is a global, systemic transition to a coexisting seizure state triggered by a local event (see Figure 1B). We find that such a global transition is enabled by an increase in excitability of the surrounding tissue, essentially creating a seizure supporting surrounding. In our simulations, the difference in surrounding tissue excitability also offers a simple explanation of the clinically observed difference in surgical outcomes. Finally, we demonstrate how changes in tissue excitability could be elucidated in principle using active stimulation.<br \/>\nWe conclude that the excitability of the tissue surrounding the seizure core plays a determining role in the seizure onset pattern, as well as in the surgical outcome.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u3053\u306e\u767a\u8868\u3067\u306f\uff0c\u3066\u3093\u304b\u3093\u306e\u767a\u4f5c\u767a\u751f\u6642\u306e\u8133\u6d3b\u52d5\u3092EEG\u3067\u8a08\u6e2c\u3057\u7814\u7a76\u3057\u3066\u3044\u307e\u3057\u305f\uff0e\u307e\u305f\uff0c\u305d\u306e\u6642\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u5909\u5316\u3092\u898b\u3066\u3044\u307e\u3057\u305f\uff0e\u3066\u3093\u304b\u3093\u306e\u767a\u751f\u306b\u306f\u7279\u5b9a\u306e\u7d30\u80de\u304c\u8d77\u56e0\u3057\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u8ff0\u3079\u3066\u3044\u307e\u3057\u305f\uff0e\u3066\u3093\u304b\u3093\u306f\u591a\u304f\u306e\u65b9\u304c\u304b\u304b\u3063\u3066\u3044\u308b\u75c5\u6c17\u3067\u3082\u3042\u308b\u306e\u3067\uff0c\u7814\u7a76\u304c\u9032\u307f\u5c11\u3057\u3067\u3082QOL\u304c\u9ad8\u304f\u306a\u308b\u3068\u3044\u3044\u3068\u601d\u3063\u3066\u3044\u308b\u306e\u3067\uff0c\u3053\u306e\u3088\u3046\u306a\u7814\u7a76\u3092\u3057\u3066\u3044\u308b\u767a\u8868\u8005\u304c\u4ed6\u306b\u3082\u3044\u3066\u8208\u5473\u3092\u6301\u3063\u3066\u805e\u304f\u3053\u3068\u304c\u3067\u304d\u307e\u3057\u305f\uff0e<br \/>\n&nbsp;<br \/>\n\u53c2\u8003\u6587\u732e<br \/>\n(1) S. Tsujimoto, T. Yamamoto, H. Kawaguchi, H. Koizumi and T. Sawaguchi, \u201cPrefrontal cortical activation associated with working memory in adults and preschool<br \/>\nchildren: an event-related optical topography study,\u201d Neuroimage, vol. 1, no. 21,<\/p>\n<ol start=\"2004\">\n<li>283\u2013290, 2004.<\/li>\n<\/ol>\n<p>&nbsp;<br \/>\n(2) M. Hofmann, M. Herrmann, I. Dan, H. Obrig, M. Conrad, L. Kuchinke, A. Jacobs<br \/>\nand A. Fallgatter, \u201cDifferential activation of frontal and parietal regions during visual<br \/>\nword recognition: an optical topography study,\u201d Neuroimage, vol. 3, no. 40, pp.<br \/>\n1340\u20131349, 2008.<br \/>\n&nbsp;<br \/>\n(3) T. Sano, D. Tsuzuki, I. Dan, H. Dan, H. Yokota, K. Oguro and E. Watanabe, \u201cAdaptive hemodynamic response function to optimize differential temporal information<br \/>\nof hemoglobin signals in functional near-infrared spectroscopy,\u201d Complex Medical<br \/>\nEngineering (CME), vol. 1, no. 1, pp. 788\u2013792, 2012.<br \/>\n&nbsp;<br \/>\n(4) I. Dan, T. Sano, H. Dan and E. Watanabe, \u201cOptimizing the general linear model for<br \/>\nfunctional near-infrared spectroscopy: an adaptive hemodynamic response function<br \/>\napproach,\u201d Neurophoton, vol. 1, no. 1, pp. 015004\u2013015004, 2014.<br \/>\n&nbsp;<br \/>\n&nbsp;<br \/>\n&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u65e5\u672c\u5149\u8133\u6a5f\u80fd\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a\u304c\u3001\u661f\u9675\u4f1a\u9928\u3067\u958b\u50ac\u3055\u308c\u307e\u3057\u305f\u3002 \u7814\u7a76\u5ba4\u304b\u3089\u306f fNIRS\u306b\u3088\u308b\u7791\u60f3\u4e2d\u306e\u8133\u6d3b\u52d5\u306e\u8a08\u6e2c\u3000\u85e4\u4e95\u8056\u9999\u3000(B4) \u304c\u767a\u8868\u3057\u307e\u3057\u305f\u3002<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-3573","post","type-post","status-publish","format-standard","hentry","category-6"],"_links":{"self":[{"href":"https:\/\/is.doshisha.ac.jp\/news\/index.php?rest_route=\/wp\/v2\/posts\/3573","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/is.doshisha.ac.jp\/news\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/is.doshisha.ac.jp\/news\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/is.doshisha.ac.jp\/news\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/is.doshisha.ac.jp\/news\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3573"}],"version-history":[{"count":0,"href":"https:\/\/is.doshisha.ac.jp\/news\/index.php?rest_route=\/wp\/v2\/posts\/3573\/revisions"}],"wp:attachment":[{"href":"https:\/\/is.doshisha.ac.jp\/news\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3573"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/is.doshisha.ac.jp\/news\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3573"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/is.doshisha.ac.jp\/news\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3573"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}